Role of TNF–TNF receptor 2 signal in regulatory T cells and its therapeutic implications
Tumor necrosis factor α (TNFα) is a pleiotropic cytokine which signals through TNF receptor
1 (TNFR1) and TNF receptor 2 (TNFR2). Emerging evidence has demonstrated that TNFR1 …
1 (TNFR1) and TNF receptor 2 (TNFR2). Emerging evidence has demonstrated that TNFR1 …
Inflammatory modulation of HSCs: viewing the HSC as a foundation for the immune response
KY King, MA Goodell - Nature Reviews Immunology, 2011 - nature.com
Cells of the innate and adaptive immune systems are the progeny of a variety of
haematopoietic precursors, the most primitive of which is the haematopoietic stem cell …
haematopoietic precursors, the most primitive of which is the haematopoietic stem cell …
Regulation of hematopoietic and leukemic stem cells by the immune system
C Riether, CM Schürch, AF Ochsenbein - Cell death & differentiation, 2015 - nature.com
Hematopoietic stem cells (HSCs) are rare, multipotent cells that generate via progenitor and
precursor cells of all blood lineages. Similar to normal hematopoiesis, leukemia is also …
precursor cells of all blood lineages. Similar to normal hematopoiesis, leukemia is also …
Chimerism and tolerance without GVHD or engraftment syndrome in HLA-mismatched combined kidney and hematopoietic stem cell transplantation
J Leventhal, M Abecassis, J Miller, L Gallon… - Science translational …, 2012 - science.org
The toxicity of chronic immunosuppressive agents required for organ transplant
maintenance has prompted investigators to pursue approaches to induce immune tolerance …
maintenance has prompted investigators to pursue approaches to induce immune tolerance …
Inflammatory signals regulate hematopoietic stem cells
Hematopoietic stem cells (HSCs) are the progenitors of all blood and immune cells, yet their
role in immunity is not well understood. Most studies have focused on the ability of …
role in immunity is not well understood. Most studies have focused on the ability of …
Цитокины в патогенезе и лечении заболеваний человека
АС Симбирцев - 2018 - elibrary.ru
В монографии приведены сведения по роли цитокинов в регуляции физиологических
процессов, защитных реакций организма и в патогенезе иммунопатологических …
процессов, защитных реакций организма и в патогенезе иммунопатологических …
Pro-inflammatory cytokines: emerging players regulating HSC function in normal and diseased hematopoiesis
C Mirantes, E Passegué, EM Pietras - Experimental cell research, 2014 - Elsevier
Hematopoiesis is the hierarchical process in which all lineages of blood cells are produced
by self-renewing hematopoietic stem cells (HSCs) in the bone marrow (BM). While the …
by self-renewing hematopoietic stem cells (HSCs) in the bone marrow (BM). While the …
[HTML][HTML] Daily onset of light and darkness differentially controls hematopoietic stem cell differentiation and maintenance
Hematopoietic stem and progenitor cells (HSPCs) tightly couple maintenance of the bone
marrow (BM) reservoir, including undifferentiated long-term repopulating hematopoietic …
marrow (BM) reservoir, including undifferentiated long-term repopulating hematopoietic …
TNF receptor 2 and disease: autoimmunity and regenerative medicine
DL Faustman, M Davis - Frontiers in immunology, 2013 - frontiersin.org
The regulatory cytokine tumor necrosis factor (TNF) exerts its effects through two receptors:
TNFR1 and TNFR2. Defects in TNFR2 signaling are evident in a variety of autoimmune …
TNFR1 and TNFR2. Defects in TNFR2 signaling are evident in a variety of autoimmune …
The cytokine network in acute myeloid leukemia
M Luciano, PW Krenn, J Horejs-Hoeck - Frontiers in immunology, 2022 - frontiersin.org
Acute myeloid leukemia (AML) is a highly heterogeneous malignancy of the blood and bone
marrow, characterized by clonal expansion of myeloid stem and progenitor cells and rapid …
marrow, characterized by clonal expansion of myeloid stem and progenitor cells and rapid …