Cognition and dementia in older patients with epilepsy
With advances in healthcare and an ageing population, the number of older adults with
epilepsy is set to rise substantially across the world. In developed countries the highest …
epilepsy is set to rise substantially across the world. In developed countries the highest …
[HTML][HTML] Blood-based biomarkers of cerebral small vessel disease
Age-associated cerebral small vessel disease (CSVD) represents a clinically heterogenous
condition, arising from diverse microvascular mechanisms. These lead to chronic …
condition, arising from diverse microvascular mechanisms. These lead to chronic …
Longitudinal changes in the cerebral cortex functional organization of healthy elderly
Healthy aging is accompanied by disruptions in the functional modular organization of the
human brain. Cross-sectional studies have shown age-related reductions in the functional …
human brain. Cross-sectional studies have shown age-related reductions in the functional …
Distinct network topology in Alzheimer's disease and behavioral variant frontotemporal dementia
Background Alzheimer's disease (AD) and behavioral variant frontotemporal dementia
(bvFTD) cause distinct atrophy and functional disruptions within two major intrinsic brain …
(bvFTD) cause distinct atrophy and functional disruptions within two major intrinsic brain …
Deep phenotyping of Alzheimer's disease leveraging electronic medical records identifies sex-specific clinical associations
AS Tang, T Oskotsky, S Havaldar, WG Mantyh… - Nature …, 2022 - nature.com
Alzheimer's Disease (AD) is a neurodegenerative disorder that is still not fully understood.
Sex modifies AD vulnerability, but the reasons for this are largely unknown. We utilize two …
Sex modifies AD vulnerability, but the reasons for this are largely unknown. We utilize two …
Longitudinal functional brain network reconfiguration in healthy aging
B Malagurski, F Liem, J Oschwald… - Human Brain …, 2020 - Wiley Online Library
Healthy aging is associated with changes in cognitive performance and functional brain
organization. In fact, cross‐sectional studies imply lower modularity and significant …
organization. In fact, cross‐sectional studies imply lower modularity and significant …
Alterations in brain network topology and structural-functional connectome coupling relate to cognitive impairment
According to the network-based neurodegeneration hypothesis, neurodegenerative
diseases target specific large-scale neural networks, such as the default mode network, and …
diseases target specific large-scale neural networks, such as the default mode network, and …
Distinct BOLD variability changes in the default mode and salience networks in Alzheimer's disease spectrum and associations with cognitive decline
Optimal levels of intrinsic Blood-Oxygenation-Level-Dependent (BOLD) signal variability
(variability hereafter) are important for normative brain functioning. However, it remains …
(variability hereafter) are important for normative brain functioning. However, it remains …
Time-efficient physical training for enhancing cardiovascular function in midlife and older adults: promise and current research gaps
DH Craighead, TC Heinbockel… - Journal of Applied …, 2019 - journals.physiology.org
Cardiovascular diseases (CVD) remain the leading cause of death in developed societies,
and “midlife”(50–64 yr) and older (65+) men and women bear the great majority of the …
and “midlife”(50–64 yr) and older (65+) men and women bear the great majority of the …
Indoor incense burning impacts cognitive functions and brain functional connectivity in community older adults
To investigate (1) the effects of indoor incense burning upon cognition over 3 years;(2) the
associations between indoor incense burning with the brain's structure and functional …
associations between indoor incense burning with the brain's structure and functional …