Colorectal cancer (CRC) is one of the most common aggressive carcinoma types worldwide,
characterized by unfavorable curative effect and poor prognosis. Epidemiological data re …

Consistent evidence associates IGF-1 deficiency and metabolic syndrome. In this review, we
will focus on the metabolic effects of IGF-1, the concept of metabolic syndrome and its …

Background Time-restricted feeding (TRF) is a form of intermittent fasting, which is beneficial
for weight loss and cardiometabolic health. Polycystic ovary syndrome (PCOS) is one of the …

Dysregulated growth hormone (GH) hypersecretion is usually caused by a GH-secreting
pituitary adenoma and leads to acromegaly—a disorder of disproportionate skeletal, tissue …

Growth hormone (GH) is important for promotion of somatic growth and the regulation of
substrate metabolism. Metabolic action of GH occurs in multiple tissues including the liver …

Obesity and nutrient homeostasis are linked by mechanisms that are not fully elucidated.
Here we describe a secreted protein, adropin, encoded by a gene, Energy Homeostasis …

Adropin is a secreted peptide that improves hepatic steatosis and glucose homeostasis
when administered to diet‐induced obese mice. It is not clear if adropin is a peptide …

Growth hormone (GH) and insulin-like growth factor I (IGF-I) measurements are widely used
in the diagnosis of disorders of GH secretion, evaluation of children with short stature from …

Current therapies for type 1 diabetes (T1D) involve insulin replacement or transplantation of
insulin-secreting tissue, both of which suffer from numerous limitations and complications …

Growth hormone (GH) and insulin-like growth factor-1 (IGF-I) are pleiotropic hormones with
important roles in lifespan. They promote growth, anabolic actions, and body maintenance …