[HTML][HTML] Medial and orbital frontal cortex in decision-making and flexible behavior
The medial frontal cortex and adjacent orbitofrontal cortex have been the focus of
investigations of decision-making, behavioral flexibility, and social behavior. We review …
investigations of decision-making, behavioral flexibility, and social behavior. We review …
[HTML][HTML] Deep reinforcement learning and its neuroscientific implications
The emergence of powerful artificial intelligence (AI) is defining new research directions in
neuroscience. To date, this research has focused largely on deep neural networks trained …
neuroscience. To date, this research has focused largely on deep neural networks trained …
Balancing exploration and exploitation with information and randomization
Explore-exploit decisions require us to trade off the benefits of exploring unknown options to
learn more about them, with exploiting known options, for immediate reward. Such decisions …
learn more about them, with exploiting known options, for immediate reward. Such decisions …
Multidimensional processing in the amygdala
KM Gothard - Nature Reviews Neuroscience, 2020 - nature.com
Brain-wide circuits that coordinate affective and social behaviours intersect in the amygdala.
Consequently, amygdala lesions cause a heterogeneous array of social and non-social …
Consequently, amygdala lesions cause a heterogeneous array of social and non-social …
Reinforcement-learning in fronto-striatal circuits
B Averbeck, JP O'Doherty - Neuropsychopharmacology, 2022 - nature.com
We review the current state of knowledge on the computational and neural mechanisms of
reinforcement-learning with a particular focus on fronto-striatal circuits. We divide the …
reinforcement-learning with a particular focus on fronto-striatal circuits. We divide the …
[HTML][HTML] The neurocomputational bases of explore-exploit decision-making
J Hogeveen, TS Mullins, JD Romero, E Eversole… - Neuron, 2022 - cell.com
Flexible decision-making requires animals to forego immediate rewards (exploitation) and
try novel choice options (exploration) to discover if they are preferable to familiar …
try novel choice options (exploration) to discover if they are preferable to familiar …
[HTML][HTML] Prefrontal cortex predicts state switches during reversal learning
R Bartolo, BB Averbeck - Neuron, 2020 - cell.com
Reinforcement learning allows organisms to predict future outcomes and to update their
beliefs about value in the world. The dorsal-lateral prefrontal cortex (dlPFC) integrates …
beliefs about value in the world. The dorsal-lateral prefrontal cortex (dlPFC) integrates …
[HTML][HTML] Dopaminergic modulation of the exploration/exploitation trade-off in human decision-making
Involvement of dopamine in regulating exploration during decision-making has long been
hypothesized, but direct causal evidence in humans is still lacking. Here, we use a …
hypothesized, but direct causal evidence in humans is still lacking. Here, we use a …
Humans adaptively resolve the explore-exploit dilemma under cognitive constraints: Evidence from a multi-armed bandit task
When navigating uncertain worlds, humans must balance exploring new options versus
exploiting known rewards. Longer horizons and spatially structured option values …
exploiting known rewards. Longer horizons and spatially structured option values …
From exploration to exploitation: A shifting mental mode in late life development
Changes in cognition, affect, and brain function combine to promote a shift in the nature of
mentation in older adulthood, favoring exploitation of prior knowledge over exploratory …
mentation in older adulthood, favoring exploitation of prior knowledge over exploratory …