Nonviral nanoparticles have emerged as an attractive alternative to viral vectors for gene
therapy applications, utilizing a range of lipid‐based, polymeric, and inorganic materials …

Background Chimeric antigen receptor (CAR) T cells have achieved remarkable responses
in patients with hematological malignancies; however, the potential of this therapeutic …

Cerebral ischemia is a serious disease characterized by brain tissue ischemia and hypoxic
necrosis caused by the blockage of blood vessels within the central nervous system …

Multinucleated microglia have been observed in contexts associated with infection,
inflammation, and aging. Though commonly linked to pathological conditions, the larger cell …

Monoclonal antibodies (mAbs) have high binding specificity and affinity, making them
attractive for treating brain diseases. However, their effectiveness is limited by poor blood …

Both exogenous gaseous and liquid forms of formaldehyde (FA) can induce depressive-like
behaviors in both animals and humans. Stress and neuronal excitation can elicit brain FA …

The investigation of neuroendocrine systems often requires the delivery of drugs, viruses, or
other experimental agents directly into the brains of mice. An intracerebroventricular (ICV) …

Flowrate control in flexible bioelectronics with targeted drug delivery capabilities is essential
to ensure timely and safe delivery. For neuroscience and pharmacogenetics studies in small …

Highly efficient adeno associated viruses (AAVs) targeting the central nervous system (CNS)
are needed to deliver safe and effective therapies for inherited neurological disorders. The …

Significant health risks are posed by meningitis due to its rapid progression, and challenges
are encountered in intravenous antibiotic administration, especially in crossing the blood …