Red blood cell hitchhiking: a novel approach for vascular delivery of nanocarriers

JS Brenner, S Mitragotri… - Annual review of …, 2021 - annualreviews.org
Red blood cell (RBC) hitchhiking is a method of drug delivery that can increase drug
concentration in target organs by orders of magnitude. In RBC hitchhiking, drug-loaded …

Putting copper into action: copper‐impregnated products with potent biocidal activities

G Borkow, J Gabbay - The FASEB journal, 2004 - Wiley Online Library
Copper ions, either alone or in copper complexes, have been used for centuries to disinfect
liquids, solids, and human tissue. Today copper is used as a water purifier, algaecide …

[HTML][HTML] Complement evasion strategies of viruses: an overview

P Agrawal, R Nawadkar, H Ojha, J Kumar… - Frontiers in …, 2017 - frontiersin.org
Being a major first line of immune defense, the complement system keeps a constant vigil
against viruses. Its ability to recognize large panoply of viruses and virus-infected cells, and …

[PDF][PDF] Duffy antigen receptor for chemokines mediates trans-infection of HIV-1 from red blood cells to target cells and affects HIV-AIDS susceptibility

W He, S Neil, H Kulkarni, E Wright, BK Agan… - Cell host & …, 2008 - cell.com
Duffy antigen receptor for chemokines (DARC) expressed on red blood cells (RBCs)
influences plasma levels of HIV-1-suppressive and proinflammatory chemokines such as …

Platelets from HIV-infected individuals on antiretroviral drug therapy with poor CD4+ T cell recovery can harbor replication-competent HIV despite viral suppression

F Real, C Capron, A Sennepin, R Arrigucci… - Science translational …, 2020 - science.org
In addition to hemostasis, human platelets have several immune functions and interact with
infectious pathogens including HIV in vitro. Here, we report that platelets from HIV-infected …

Pathogen-reduction systems for blood components: the current position and future trends

J Seghatchian, G de Sousa - Transfusion and apheresis science, 2006 - Elsevier
The current multi-layered interventional approaches to blood safety have dramatically
reduced the risk of viral contamination of blood components. Nowadays most of the residual …

Pathogen inactivation technology: cleansing the blood supply

HG Klein - Journal of internal medicine, 2005 - Wiley Online Library
Klein HG (The Johns Hopkins School of Medicine and Warren G. Magnuson Clinical Center,
National Institutes of Health, Bethesda, MD, USA). Pathogen inactivation technology …

CD71+ Erythroid Cells Exacerbate HIV-1 Susceptibility, Mediate trans-Infection, and Harbor Infective Viral Particles

A Namdar, G Dunsmore, S Shahbaz, P Koleva, L Xu… - MBio, 2019 - Am Soc Microbiol
ABSTRACT CD71+ erythroid cells (CECs) have a wide range of immunomodulatory
properties. Here, we show that CECs are expanded in the peripheral blood of HIV patients …

HIV‐1 persistence, viral reservoir, and the central nervous system in the HAART era

O Lambotte, K Deiva, M Tardieu - Brain pathology, 2003 - Wiley Online Library
HAART therapy has led to a significant reduction of general and neurological morbidity, and
mortality among HIV‐1 infected patients. It can also decrease HIV‐1 RNA titres in plasma …

The good and evil of complement activation in HIV-1 infection

Q Yu, R Yu, X Qin - Cellular & molecular immunology, 2010 - nature.com
The complement system, a key component of innate immunity, is a first-line defender against
foreign pathogens such as HIV-1. The role of the complement system in HIV-1 pathogenesis …