Ca2+ dynamics in interstitial cells: foundational mechanisms for the motor patterns in the gastrointestinal tract
The gastrointestinal (GI) tract displays multiple motor patterns that move nutrients and
wastes through the body. Smooth muscle cells (SMCs) provide the forces necessary for GI …
wastes through the body. Smooth muscle cells (SMCs) provide the forces necessary for GI …
Sex neurosteroids: Hormones made by the brain for the brain
L Fester, GM Rune - Neuroscience Letters, 2021 - Elsevier
In general, hippocampal neurons are capable of synthesizing sex steroids de novo from
cholesterol, since the brain is equipped with all the enzymes required for the synthesis of …
cholesterol, since the brain is equipped with all the enzymes required for the synthesis of …
Cholesterol‐promoted synaptogenesis requires the conversion of cholesterol to estradiol in the hippocampus
L Fester, L Zhou, A Bütow, C Huber… - …, 2009 - Wiley Online Library
Cholesterol of glial origin promotes synaptogenesis (Mauch et al.,(2001) Science 294: 1354–
1357). Because in the hippocampus local estradiol synthesis is essential for …
1357). Because in the hippocampus local estradiol synthesis is essential for …
Interstitial cells of Cajal (ICC) and gastrointestinal stromal tumor (GIST): facts, speculations, and myths
KW Min, M Leabu - Journal of cellular and molecular medicine, 2006 - Wiley Online Library
Interstitial cells of Cajal (ICC) is a peculiar cell network composed of cells having processes
described by the eminent Spanish neuroanatomist of the 19th century, S. Ramon y Cajal …
described by the eminent Spanish neuroanatomist of the 19th century, S. Ramon y Cajal …
Depletion of membrane cholesterol eliminates the Ca2+‐activated component of outward potassium current and decreases membrane capacitance in rat uterine …
Changes in membrane cholesterol content have potent effects on cell signalling and
contractility in rat myometrium and other smooth muscles. We have previously shown that …
contractility in rat myometrium and other smooth muscles. We have previously shown that …
Estrogen synthesis in the hippocampus
L Fester, J Prange-Kiel, H Jarry, GM Rune - Cell and tissue research, 2011 - Springer
Estradiol plays essential roles in the modulation of synaptic plasticity and neuroprotection in
males as well as in females, as has been shown particularly in the hippocampus. Although it …
males as well as in females, as has been shown particularly in the hippocampus. Although it …
Large conductance, calcium-and voltage-gated potassium (BK) channels: regulation by cholesterol
Cholesterol (CLR) is an essential component of eukaryotic plasma membranes. CLR
regulates the membrane physical state, microdomain formation and the activity of membrane …
regulates the membrane physical state, microdomain formation and the activity of membrane …
Caveolae and calcium handling, a review and a hypothesis
EE Daniel, A El‐Yazbi, WJ Cho - Journal of cellular and …, 2006 - Wiley Online Library
Caveolae are associated with molecules crucial for calcium handling. This review considers
the roles of caveolae in calcium handling for smooth muscle and interstitial cells of Cajal …
the roles of caveolae in calcium handling for smooth muscle and interstitial cells of Cajal …
Proteins of interstitial cells of Cajal and intestinal smooth muscle, colocalized with caveolin-1
WJ Cho, EE Daniel - American Journal of Physiology …, 2005 - journals.physiology.org
The murine jejunum and lower esophageal sphincter (LES) were examined to determine the
locations of various signaling molecules and their colocalization with caveolin-1 and one …
locations of various signaling molecules and their colocalization with caveolin-1 and one …
Matrix metalloproteinase‐2, caveolins, focal adhesion kinase and c‐Kit in cells of the mouse myocardium
Abstract Matrix metalloproteinase‐2 (MMP‐2) may play roles at intracellular and
extracellular sites of the heart in ischaemia/reperfusion injury. Caveolins (Cav‐1,‐2 and‐3) …
extracellular sites of the heart in ischaemia/reperfusion injury. Caveolins (Cav‐1,‐2 and‐3) …