Dissecting autism and schizophrenia through neuroimaging genomics
Neuroimaging genomic studies of autism spectrum disorder and schizophrenia have mainly
adopted a 'top-down'approach, beginning with the behavioural diagnosis, and moving down …
adopted a 'top-down'approach, beginning with the behavioural diagnosis, and moving down …
Evaluation of brain-body health in individuals with common neuropsychiatric disorders
Importance Physical health and chronic medical comorbidities are underestimated,
inadequately treated, and often overlooked in psychiatry. A multiorgan, systemwide …
inadequately treated, and often overlooked in psychiatry. A multiorgan, systemwide …
Evidence for embracing normative modeling
In this work, we expand the normative model repository introduced in Rutherford et al.,
2022a to include normative models charting lifespan trajectories of structural surface area …
2022a to include normative models charting lifespan trajectories of structural surface area …
Resolving the delusion paradox
P Petrovic, P Sterzer - Schizophrenia Bulletin, 2023 - academic.oup.com
Abstract Background and Hypothesis The neurocomputational framework of predictive
processing (PP) provides a promising approach to explaining delusions, a key symptom of …
processing (PP) provides a promising approach to explaining delusions, a key symptom of …
Association of structural magnetic resonance imaging measures with psychosis onset in individuals at clinical high risk for developing psychosis: an ENIGMA working …
M Jalbrzikowski, RA Hayes, SJ Wood… - JAMA …, 2021 - jamanetwork.com
Importance The ENIGMA clinical high risk (CHR) for psychosis initiative, the largest pooled
neuroimaging sample of individuals at CHR to date, aims to discover robust neurobiological …
neuroimaging sample of individuals at CHR to date, aims to discover robust neurobiological …
Virtual histology of cortical thickness and shared neurobiology in 6 psychiatric disorders
Importance Large-scale neuroimaging studies have revealed group differences in cortical
thickness across many psychiatric disorders. The underlying neurobiology behind these …
thickness across many psychiatric disorders. The underlying neurobiology behind these …
Genetic association between schizophrenia and cortical brain surface area and thickness
Importance Schizophrenia is a complex heritable disorder associated with many genetic
variants, each with a small effect. While cortical differences between patients with …
variants, each with a small effect. While cortical differences between patients with …
Differential effects of early or late exposure to prenatal maternal immune activation on mouse embryonic neurodevelopment
E Guma, M Bordeleau… - Proceedings of the …, 2022 - National Acad Sciences
Exposure to maternal immune activation (MIA) in utero is a risk factor for
neurodevelopmental and psychiatric disorders. MIA-induced deficits in adolescent and adult …
neurodevelopmental and psychiatric disorders. MIA-induced deficits in adolescent and adult …
Using machine learning and structural neuroimaging to detect first episode psychosis: reconsidering the evidence
Despite the high level of interest in the use of machine learning (ML) and neuroimaging to
detect psychosis at the individual level, the reliability of the findings is unclear due to …
detect psychosis at the individual level, the reliability of the findings is unclear due to …
Normative modeling of brain morphometry in clinical high risk for psychosis
Importance The lack of robust neuroanatomical markers of psychosis risk has been
traditionally attributed to heterogeneity. A complementary hypothesis is that variation in …
traditionally attributed to heterogeneity. A complementary hypothesis is that variation in …