Diagnostics, risk factors, treatment and outcomes of acute kidney injury in a new paradigm
Acute kidney injury (AKI) is a common clinical condition among patients admitted in the
hospitals. The condition is associated with both increased short-term and long-term …
hospitals. The condition is associated with both increased short-term and long-term …
Neutrophil-to-lymphocyte ratio is a marker for acute kidney injury progression and mortality in critically ill populations: a population-based, multi-institutional study
Backgrounds Neutrophil-to-lymphocyte ratio (NLR), a surrogate marker of systemic
response to physiological stress, is used for prognosis prediction in many diseases …
response to physiological stress, is used for prognosis prediction in many diseases …
Plasma Metabolites–Based Prediction in Cardiac Surgery–Associated Acute Kidney Injury
H Cui, S Shu, Y Li, X Yan, X Chen, Z Chen… - Journal of the …, 2021 - Am Heart Assoc
Background Cardiac surgery–associated acute kidney injury (CSA‐AKI) is a common
postoperative complication following cardiac surgery. Currently, there are no reliable …
postoperative complication following cardiac surgery. Currently, there are no reliable …
[HTML][HTML] Current update on theranostic roles of cyclophilin A in kidney diseases
S Hadpech, V Thongboonkerd - Theranostics, 2022 - ncbi.nlm.nih.gov
Cyclophilin A (CyPA) or peptidylprolyl isomerase A (PPIA), an immunophilin with peptidyl-
prolyl cis/trans isomerase (PPIase) activity, is an abundant cellular protein widely expressed …
prolyl cis/trans isomerase (PPIase) activity, is an abundant cellular protein widely expressed …
Cyclophilin A promotes inflammation in acute kidney injury but not in renal fibrosis
KG Leong, E Ozols, J Kanellis… - International journal of …, 2020 - mdpi.com
Cyclophilin A (CypA) is a highly abundant protein in the cytoplasm of most mammalian cells.
Beyond its homeostatic role in protein folding, CypA is a Damage-Associated Molecular …
Beyond its homeostatic role in protein folding, CypA is a Damage-Associated Molecular …
Urinary cyclophilin A as an early marker of chronic kidney disease with underlying type 2 diabetes
P Chatchawal, P Tippayawat, T Somdee… - Scientific Reports, 2024 - nature.com
Cyclophilin A (CypA) is a novel renal inflammation biomarker, with levels altered in various
diseases, particularly in patients with diabetes mellitus (DM) and kidney damage. This study …
diseases, particularly in patients with diabetes mellitus (DM) and kidney damage. This study …
Exploratory investigation of the plasma proteome associated with the endotheliopathy of trauma
JD Krocker, KH Lee, HH Henriksen… - International Journal of …, 2022 - mdpi.com
Background: The endotheliopathy of trauma (EoT) is associated with increased mortality
following injury. Herein, we describe the plasma proteome related to EoT in order to provide …
following injury. Herein, we describe the plasma proteome related to EoT in order to provide …
Urinary cyclophilin A as marker of tubular cell death and kidney injury
R Cabello, M Fontecha-Barriuso, D Martin-Sanchez… - Biomedicines, 2021 - mdpi.com
Background: Despite the term acute kidney injury (AKI), clinical biomarkers for AKI reflect
function rather than injury and independent markers of injury are needed. Tubular cell death …
function rather than injury and independent markers of injury are needed. Tubular cell death …
[HTML][HTML] 亲环蛋白A 和CD147 与肾脏疾病研究进展
陶丽, 苏华 - Advances in Clinical Medicine, 2022 - hanspub.org
亲环蛋白A (cyclophilin A, CypA) 在体内普遍表达, 主要位于细胞内, 在受到感染,
缺氧和氧化应激等刺激时, 可以分泌到各种细胞类型的细胞外环境中. CD147 …
缺氧和氧化应激等刺激时, 可以分泌到各种细胞类型的细胞外环境中. CD147 …
[HTML][HTML] Copeptin concentration following cardiac surgery as a prognostic marker of postoperative acute kidney injury: a prospective cohort study
K Yamashita, T Abe, Y Hayata, T Hirose… - Journal of Thoracic …, 2020 - ncbi.nlm.nih.gov
Background Copeptin, the C-terminal portion of the arginine vasopressin precursor, is a
novel candidate biomarker. This study investigated the prognostic value of copeptin levels …
novel candidate biomarker. This study investigated the prognostic value of copeptin levels …