Glutathione responsive polymers and their application in drug delivery systems
Materials which respond to biological cues are the subject of intense research interest due
to their possible application in smart drug delivery vehicles. In particular, novel polymers …
to their possible application in smart drug delivery vehicles. In particular, novel polymers …
Polypeptides–drug conjugates for anticancer therapy
Polypeptides are an important class of biodegradable polymers that have been widely used
in drug delivery field. Owing to the controllable synthesis and robust side chain …
in drug delivery field. Owing to the controllable synthesis and robust side chain …
Polymer‐based drug delivery systems for cancer treatment
X Guo, L Wang, X Wei, S Zhou - Journal of Polymer Science …, 2016 - Wiley Online Library
This review is focused on the chemical design and synthesis of polymer‐based drug
delivery systems, in particular with stimuli‐responsive nanoplatforms for cancer treatment …
delivery systems, in particular with stimuli‐responsive nanoplatforms for cancer treatment …
Redox-sensitive hydroxyethyl starch–doxorubicin conjugate for tumor targeted drug delivery
H Hu, Y Li, Q Zhou, Y Ao, C Yu, Y Wan… - … applied materials & …, 2016 - ACS Publications
Doxorubicin (DOX) is one of the most potent anticancer agents in cancer chemotherapy, but
the clinical use of DOX is restricted by its severe side effects caused by nonspecific delivery …
the clinical use of DOX is restricted by its severe side effects caused by nonspecific delivery …
Disulfide‐based self‐Immolative linkers and functional bioconjugates for biological applications
It is of vital importance to reversibly mask and selectively activate bioactive agents for
advanced therapeutic and diagnostic purposes, aiming to efficiently suppress background …
advanced therapeutic and diagnostic purposes, aiming to efficiently suppress background …
Perspectives about self-immolative drug delivery systems
Self-immolative drug delivery system is one of the delivery systems, which have drawn
attention, in recent research, highlighting the improvement they generate in drug selectivity …
attention, in recent research, highlighting the improvement they generate in drug selectivity …
Reversible cross-linked thermoresponsive polycaprolactone micelles for enhanced stability and controlled release
Thermoresponsive amphiphilic poly (ε-caprolactone) s (PCL) s are excellent candidates for
drug delivery due to their biodegradability, biocompatibility, and controlled release …
drug delivery due to their biodegradability, biocompatibility, and controlled release …
Stimulus‐Responsive Nano‐Prodrug Strategies for Cancer Therapy: A Focus on Camptothecin Delivery
B Chu, H Deng, T Niu, Y Qu, Z Qian - Small Methods, 2024 - Wiley Online Library
Camptothecin (CPT) is a highly cytotoxic molecule with excellent antitumor activity against
various cancers. However, its clinical application is severely limited by poor water solubility …
various cancers. However, its clinical application is severely limited by poor water solubility …
Recent advances in stimuli-responsive polymeric micelles via click chemistry
Y Dai, X Chen, X Zhang - Polymer Chemistry, 2019 - pubs.rsc.org
Stimuli-responsive polymeric micelles have served as an emerging and interesting platform
for poorly soluble drug delivery towards cancer therapy in response to exogenous stimuli …
for poorly soluble drug delivery towards cancer therapy in response to exogenous stimuli …
Multifunctional polymeric prodrug with simultaneous conjugating camptothecin and doxorubicin for pH/reduction dual-responsive drug delivery
S Dong, Y Sun, J Liu, L Li, J He… - ACS applied materials …, 2019 - ACS Publications
Amphiphilic polymeric prodrugs show improved therapeutic indices with respect to
traditional hydrophobic anticancer drugs because these prodrugs can self-assemble into …
traditional hydrophobic anticancer drugs because these prodrugs can self-assemble into …