Mesenchymal stem cell therapy for the treatment of inflammatory diseases: challenges, opportunities, and future perspectives
Mesenchymal stem cells (MSCs) are promising alternative agents for the treatment of
inflammatory disorders due to their immunomodulatory functions, and several clinical trials …
inflammatory disorders due to their immunomodulatory functions, and several clinical trials …
Current status of cell-based therapies for COVID-19: evidence from mesenchymal stromal cells in sepsis and ARDS
Z Xu, Y Huang, J Zhou, X Deng, W He, X Liu… - Frontiers in …, 2021 - frontiersin.org
The severe respiratory consequences of the coronavirus disease 2019 (COVID-19)
pandemic have prompted the urgent need for novel therapies. Cell-based therapies …
pandemic have prompted the urgent need for novel therapies. Cell-based therapies …
Bone marrow mesenchymal stem cells enhance angiogenesis and promote fat retention in fat grafting via polarized macrophages
J Dang, J Yang, Z Yu, L Chen, Z Zhang, K Wang… - Stem Cell Research & …, 2022 - Springer
Background Fat grafting is one of the most common soft tissue filling methods in plastic
surgery. Bone marrow mesenchymal stem cell (BM-MSC) transplantation is an effective …
surgery. Bone marrow mesenchymal stem cell (BM-MSC) transplantation is an effective …
Extracellular vesicles from adipose tissue-derived stem cells affect notch-miR148a-3p axis to regulate polarization of macrophages and alleviate sepsis in mice
X Bai, J Li, L Li, M Liu, Y Liu, M Cao, K Tao… - Frontiers in …, 2020 - frontiersin.org
Extracellular vesicles (EVs) from adipose tissue-derived stem cells have been reported to
attenuate lipopolysaccharide (LPS) induced inflammation and sepsis while the specific …
attenuate lipopolysaccharide (LPS) induced inflammation and sepsis while the specific …
Adipose-derived mesenchymal stem cells attenuate acute lung injury and improve the gut microbiota in septic rats
J Sun, X Ding, S Liu, X Duan, H Liang, T Sun - Stem Cell Research & …, 2020 - Springer
Background We hypothesized that adipose-derived mesenchymal stem cells (ADMSCs)
may ameliorate sepsis-induced acute lung injury (ALI) and change microorganism …
may ameliorate sepsis-induced acute lung injury (ALI) and change microorganism …
Bone marrow-mesenchymal stem cell-derived exosomal microRNA-141 targets PTEN and activates β-catenin to alleviate myocardial injury in septic mice
Y Pei, S Xie, J Li, B Jia - Immunopharmacology and …, 2021 - Taylor & Francis
Abstract Background Mesenchymal stem cells (MSCs) and their derived exosomes have
shown potentials in the control of myocardial dysfunction. This study aimed to reveal the …
shown potentials in the control of myocardial dysfunction. This study aimed to reveal the …
Mesenchymal stem cells-derived extracellular vesicles carrying microRNA-17 inhibits macrophage apoptosis in lipopolysaccharide-induced sepsis
Y Su, X Song, J Teng, X Zhou, Z Dong, P Li… - International …, 2021 - Elsevier
Objective Sepsis, as a disease affecting the microcirculation and tissue perfusion, results in
tissue hypoxia and multiple organ dysfunctions. Bone mesenchymal stem cell (BMSC) …
tissue hypoxia and multiple organ dysfunctions. Bone mesenchymal stem cell (BMSC) …
Curcumin preconditioning enhances the efficacy of adipose-derived mesenchymal stem cells to accelerate healing of burn wounds
Background Following recent findings from our group that curcumin preconditioning
augments the therapeutic efficacy of adipose-derived stem cells in the healing of diabetic …
augments the therapeutic efficacy of adipose-derived stem cells in the healing of diabetic …
[HTML][HTML] Sini decoction ameliorates sepsis-induced acute lung injury via regulating ACE2-Ang (1-7)-Mas axis and inhibiting the MAPK signaling pathway
Q Chen, J Liu, W Wang, S Liu, X Yang, M Chen… - Biomedicine & …, 2019 - Elsevier
Sepsis, as life-threatening organ dysfunction caused by a dysregulated host response to
infection, is characterized by the extensive release of cytokines and other mediators. Sini …
infection, is characterized by the extensive release of cytokines and other mediators. Sini …
Sini decoction alleviates E. coli induced acute lung injury in mice via equilibrating ACE-AngII-AT1R and ACE2-Ang-(1-7)-Mas axis
J Liu, Q Chen, S Liu, X Yang, Y Zhang, F Huang - Life sciences, 2018 - Elsevier
Aims Acute respiratory distress syndrome (ARDS), one of the serious form of acute lung
injury (ALI), is the primary cause of death in patients with ALI. Sini decoction (SND) is a …
injury (ALI), is the primary cause of death in patients with ALI. Sini decoction (SND) is a …