Intrapartum-related events are the third leading cause of childhood mortality worldwide and
result in one million neurodisabled survivors each year. Infants exposed to a perinatal insult …

Reactive oxygen species have a crucial role in the pathogenesis of perinatal diseases.
Exposure to inflammation, infections, or high oxygen concentrations is frequent in preterm …

Background Bright constant light levels in the NICU may have negative effects on the growth
and development of preterm infants Objective The aim of this study is to evaluate the …

The circadian rhythm derives from the integration of many signals that shape the expression
of clock-related genes in a 24-hour cycle. Biological tasks, including cell proliferation …

Oxidative stress contributes to the severity of several newborn conditions to the extent that
Saugstad coined the phrase “oxygen radical diseases of neonatology.” In order to …

Objective The relationships among sleep, circadian rhythm, and intensive care unit (ICU)-
acquired delirium are complex and remain unclear. This study aimed to examine the …

Objectives To investigate the emergence of biological rhythms in the first months of life in
human infants, by measuring age-related changes in core body temperature during night …

Considering the increased speed at which the world population is aging, sarcopenia could
become an epidemic in this century. This condition currently has no means of prevention or …

Preoperative anxiety is a major problem in paediatric surgical patients. Melatonin has been
used as a premedicant agent and data regarding effectiveness are controversial. The …

The Continuous bright light conditions to which premature infants are subjected while
hospitalized in Neonatal Intensive Care Units (NICU) can have deleterious effects in terms of …