Microglia and Parkinson's disease: footprints to pathology

E Lazdon, N Stolero, D Frenkel - Journal of Neural Transmission, 2020 - Springer
Parkinson's disease (PD) is a neurodegenerative disease associated with motor deficiency
and rigidity. The genetic risks of the disease is reported to be between 5 and 10 …

The epigenetic mechanisms involved in mitochondrial dysfunction: Implication for Parkinson's disease

Z Chen, M Rasheed, Y Deng - Brain Pathology, 2022 - Wiley Online Library
Mitochondrial dysfunction is one of the crucial factors involved in PD's pathogenicity, which
emerges from a combination of genetic and environmental factors. These factors cause …

[HTML][HTML] Consensus scoring-based virtual screening and molecular dynamics simulation of some TNF-alpha inhibitors

ID Boyenle, TI Adelusi, AT Ogunlana… - Informatics in Medicine …, 2022 - Elsevier
Abstract Inhibition of Tumor Necrosis Factor-alpha (TNF-alpha) represents a therapeutic
approach towards the management or treatment of various inflammatory diseases like …

Serum inflammatory cytokines levels and the correlation analyses in Parkinson's disease

J Fu, S Chen, J Liu, J Yang, R Ou, L Zhang… - Frontiers in Cell and …, 2023 - frontiersin.org
Objective: To investigate the serum levels of inflammatory cytokines and the correlations
with Parkinson's disease (PD) clinical symptoms. Methods: Serum levels of the cytokines …

The genetic basis of multiple system atrophy

FS Tseng, JQX Foo, AS Mai, EK Tan - Journal of Translational Medicine, 2023 - Springer
Multiple system atrophy (MSA) is a heterogenous, uniformly fatal neurodegenerative ɑ-
synucleinopathy. Patients present with varying degrees of dysautonomia, parkinsonism …

Neuropathology and pathogenesis of extrapyramidal movement disorders: a critical update—I. Hypokinetic-rigid movement disorders

KA Jellinger - Journal of Neural Transmission, 2019 - Springer
Extrapyramidal movement disorders include hypokinetic rigid and hyperkinetic or mixed
forms, most of them originating from dysfunction of the basal ganglia (BG) and their …

Diagnostic value and correlation analysis of serum cytokine levels in patients with multiple system atrophy

X Chen, S Chen, X Lai, J Fu, J Yang, R Ou… - Frontiers in Cellular …, 2024 - frontiersin.org
Background The association between cytokines in peripheral blood and clinical symptoms
of multiple system atrophy (MSA) has been explored in only a few studies with small sample …

Pathomechanisms of depression in progressive supranuclear palsy

KA Jellinger - Journal of Neural Transmission, 2023 - Springer
Depression is one of the most frequent neuropsychiatric symptoms in progressive
supranuclear palsy (PSP), a four-repeat tauopathy and most common atypical parkinsonian …

[HTML][HTML] Multiple system atrophy-a clinicopathological update

KA Jellinger - Free Neuropathology, 2020 - ncbi.nlm.nih.gov
Multiple system atrophy (MSA) is a fatal, adult-onset neurodegenerative disorder of
uncertain etiology, clinically characterized by various combinations of Levo-dopa …

通络生骨胶囊对激素性股骨头坏死模型大鼠Toll 样受体4 信号通路的影响

刘金富, 曾平, 农焦, 范思奇, 钱晓芬, 冯程钦, 雷志强… - 中国组织工程研究, 2021 - cjter.com
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工程研究|第25卷|第26期|2021年9月 通络生骨胶囊对激素性股骨头坏死模型大鼠Toll 样受体4 …