Background miRNAs, a class of small endogenous RNAs, are one of the essential
biopharmaceuticals which are in commercial spans as next-generation medicine in recent …

As a type of short noncoding RNAs, microRNA (miRNA) undoubtedly plays a crucial role in
cancer development. Since the discovery of the identity and clinical functions of miRNAs …

Congenital anomalies of the kidney and urinary tract (CAKUT) refer to a spectrum of
structural renal malformations and are the leading cause of end-stage renal disease in …

MicroRNAs (miRNAs) are small non-coding RNA molecules that regulate gene expression.
They have important roles during kidney development, homeostasis and disease. In …

Background and objective: Chronic kidney disease is a worldwide health issue which
includes not only kidney failure but also complications of reduced kidney functionality. Cyst …

Autosomal dominant polycystic kidney disease (ADPKD), caused by mutations in either
PKD1 or PKD2 genes, is one of the most common human monogenetic disorders and the …

Autosomal dominant polycystic kidney disease (ADPKD) is the most frequent genetic cause
of renal failure. Here we identify miR-17 as a target for the treatment of ADPKD. We report …

When we edited in 2007 the first issue on transient receptor potential channel in the
Handbook of Experimental Pharmacology, we were all very excited by the progress in this …

Autosomal dominant polycystic kidney disease (ADPKD), among the most common human
genetic conditions and a frequent etiology of kidney failure, is primarily caused by …

Autosomal dominant polycystic kidney disease (ADPKD) is the most common genetic renal
disease, with an estimated prevalence between 1: 1000 and 1: 2500. It is mostly caused by …