[HTML][HTML] An overview of carcinogenic heavy metal: molecular toxicity mechanism and prevention

HS Kim, YJ Kim, YR Seo - Journal of cancer prevention, 2015 - ncbi.nlm.nih.gov
Almost all heavy metals are serious toxicants as carcinogens. However, due to their
chemical and physiological properties, heavy metals are useful in industrial areas including …

Arsenic-induced oxidative stress and its reversibility

SJS Flora - Free Radical Biology and Medicine, 2011 - Elsevier
This review summarizes the literature describing the molecular mechanisms of arsenic-
induced oxidative stress, its relevant biomarkers, and its relation to various diseases …

Mechanism of arsenic carcinogenesis: an integrated approach

TG Rossman - … Research/Fundamental and Molecular Mechanisms of …, 2003 - Elsevier
Epidemiological evidence shows an association between inorganic arsenic in drinking
water and increased risk of skin, lung and bladder cancers. The lack of animal models has …

Methylated arsenicals: the implications of metabolism and carcinogenicity studies in rodents to human risk assessment

SM Cohen, LL Arnold, M Eldan, AS Lewis… - Critical reviews in …, 2006 - Taylor & Francis
Monomethylarsonic acid (MMA V) and dimethylarsinic acid (DMA V) are active ingredients in
pesticidal products used mainly for weed control. MMA V and DMA V are also metabolites of …

Arsenic in the aetiology of cancer

S Tapio, B Grosche - Mutation Research/Reviews in Mutation Research, 2006 - Elsevier
Arsenic, one of the most significant hazards in the environment affecting millions of people
around the world, is associated with several diseases including cancers of skin, lung, urinary …

Molecular mechanisms of arsenic-induced disruption of DNA repair

LM Tam, NE Price, Y Wang - Chemical research in toxicology, 2020 - ACS Publications
Exposure to arsenic in contaminated drinking water is an emerging public health problem
that impacts more than 200 million people worldwide. Accumulating lines of evidence from …

DNA–protein crosslinks: their induction, repair, and biological consequences

S Barker, M Weinfeld, D Murray - Mutation Research/Reviews in Mutation …, 2005 - Elsevier
The covalent crosslinking of proteins to DNA presents a major physical challenge to the
DNA metabolic machinery. DNA–protein crosslinks (DPCs) are induced by a variety of …

Nano‑zinc enhances gene regulation of non‑specific immunity and antioxidative status to mitigate multiple stresses in fish

N Kumar, DK Singh, NK Chandan, ST Thorat… - Scientific Reports, 2023 - nature.com
The toxicity of ammonia surged with arsenic pollution and high temperature (34° C). As
climate change enhances the pollution in water bodies, however, the aquatic animals are …

Gene-disease network analysis reveals functional modules in mendelian, complex and environmental diseases

A Bauer-Mehren, M Bundschus, M Rautschka… - PloS one, 2011 - journals.plos.org
Background Scientists have been trying to understand the molecular mechanisms of
diseases to design preventive and therapeutic strategies for a long time. For some diseases …

Arsenic-induced genotoxicity and genetic susceptibility to arsenic-related pathologies

F Faita, L Cori, F Bianchi, MG Andreassi - International journal of …, 2013 - mdpi.com
The arsenic (As) exposure represents an important problem in many parts of the World.
Indeed, it is estimated that over 100 million individuals are exposed to arsenic, mainly …