Optimizing indices of atrial fibrillation susceptibility and burden to evaluate atrial fibrillation severity, risk and outcomes

G Boriani, M Vitolo, I Diemberger… - Cardiovascular …, 2021 - academic.oup.com
Atrial fibrillation (AF) has heterogeneous patterns of presentation concerning symptoms,
duration of episodes, AF burden, and the tendency to progress towards the terminal step of …

Stroke prevention strategies in high-risk patients with atrial fibrillation

A Kotalczyk, M Mazurek, Z Kalarus… - Nature Reviews …, 2021 - nature.com
Effective stroke prevention with oral anticoagulation (OAC) is the cornerstone of the
management of patients with atrial fibrillation. The use of OAC reduces the risk of stroke and …

Predictors of device-related thrombus following percutaneous left atrial appendage occlusion

T Simard, RG Jung, K Lehenbauer, K Piayda… - Journal of the American …, 2021 - jacc.org
Background Device-related thrombus (DRT) has been considered an Achilles' heel of left
atrial appendage occlusion (LAAO). However, data on DRT prediction remain limited …

Clinical complexity domains, anticoagulation, and outcomes in patients with atrial fibrillation: a report from the GLORIA-AF registry phase II and III

GF Romiti, M Proietti, N Bonini, WY Ding… - Thrombosis and …, 2022 - thieme-connect.com
Background Clinical complexity is common in atrial fibrillation (AF) patients. We assessed
the impact of clinical complexity on oral anticoagulant (OAC) treatment patterns and major …

Associations of apixaban dose with safety and effectiveness outcomes in patients with atrial fibrillation and severe chronic kidney disease

Y Xu, AR Chang, LA Inker, M McAdams-DeMarco… - Circulation, 2023 - Am Heart Assoc
BACKGROUND: Recommendations for apixaban dosing on the basis of kidney function are
inconsistent between the US Food and Drug Administration and European Medicines …

[HTML][HTML] The effect of obesity, hypertension, diabetes mellitus, alcohol, and sleep apnea on the risk of atrial fibrillation

Z Čarná, P Osmančík - Physiological research, 2021 - ncbi.nlm.nih.gov
Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia associated with a two-
fold increase in mortality caused by a higher risk of stroke and heart failure. Currently, AF is …

Efficacy and safety of oral anticoagulants for atrial fibrillation patients with chronic kidney disease: a systematic review and meta-analysis

TM Rhee, SR Lee, EK Choi, S Oh… - Frontiers in …, 2022 - frontiersin.org
Background Data on different direct oral anticoagulants (DOACs) in atrial fibrillation (AF)
patients with renal impairment are insufficient. We aimed to perform pairwise and network …

Canagliflozin and atrial fibrillation in type 2 diabetes mellitus: A secondary analysis from the CANVAS Program and CREDENCE trial and meta‐analysis

C Li, J Yu, C Hockham, V Perkovic… - Diabetes, Obesity …, 2022 - Wiley Online Library
Aim To assess the effects of canagliflozin on the incidence of atrial fibrillation/atrial flutter
(AF/AFL) and other key cardiorenal outcomes in a pooled analysis of the CANVAS and …

Factor XI inhibitors for the prevention of cardiovascular disease: A new therapeutic approach on the horizon?

D Santagata, MP Donadini, W Ageno - Blood Reviews, 2023 - Elsevier
Anticoagulant drugs that are currently used to prevent and/or treat thrombosis have some
limitations that hinder their ability to meet specific clinical requirements. While these drugs …

Association Between Atrial Fibrillation and Diabetes-Related Complications: A Nationwide Cohort Study

S Kwon, SR Lee, EK Choi, HJ Ahn, SW Lee… - Diabetes …, 2023 - Am Diabetes Assoc
OBJECTIVE This study aimed to investigate the associations between concurrent atrial
fibrillation and diabetes-related complications among patients with diabetes. RESEARCH …