Antibacterial and antiviral functional materials: chemistry and biological activity toward tackling COVID-19-like pandemics

B Balasubramaniam, Prateek, S Ranjan… - ACS Pharmacology & …, 2020 - ACS Publications
The ongoing worldwide pandemic due to COVID-19 has created awareness toward
ensuring best practices to avoid the spread of microorganisms. In this regard, the research …

[HTML][HTML] Antimicrobial peptides: new hope in the war against multidrug resistance

J Mwangi, X Hao, R Lai, ZY Zhang - Zoological research, 2019 - ncbi.nlm.nih.gov
The discovery of antibiotics marked a golden age in the revolution of human medicine.
However, decades later, bacterial infections remain a global healthcare threat, and a return …

Alternative therapeutic strategies to treat antibiotic-resistant pathogens

CR MacNair, ST Rutherford, MW Tan - Nature Reviews Microbiology, 2024 - nature.com
Resistance threatens to render antibiotics—which are essential for modern medicine—
ineffective, thus posing a threat to human health. The discovery of novel classes of …

Integrated evolutionary analysis reveals antimicrobial peptides with limited resistance

R Spohn, L Daruka, V Lázár, A Martins… - Nature …, 2019 - nature.com
Antimicrobial peptides (AMPs) are promising antimicrobials, however, the potential of
bacterial resistance is a major concern. Here we systematically study the evolution of …

[HTML][HTML] Antimicrobial peptides–unleashing their therapeutic potential using nanotechnology

S Gera, E Kankuri, K Kogermann - Pharmacology & Therapeutics, 2022 - Elsevier
Antimicrobial peptides (AMPs) are potent, mostly cationic, and amphiphilic broad-spectrum
host defense antimicrobials that are produced by all organisms ranging from prokaryotes to …

[HTML][HTML] Microbial resistance to nanotechnologies: An important but understudied consideration using antimicrobial nanotechnologies in orthopaedic implants

Z Wu, B Chan, J Low, JJH Chu, HWD Hey, A Tay - Bioactive Materials, 2022 - Elsevier
Microbial resistance to current antibiotics therapies is a major cause of implant failure and
adverse clinical outcomes in orthopaedic surgery. Recent developments in advanced …

Biosynthesis, bioactivity, biotoxicity and applications of antimicrobial peptides for human health

D Wei, X Zhang - Biosafety and Health, 2022 - mednexus.org
Antimicrobial peptides (AMPs) are the natural antibiotics recognized for their broad-
spectrum resistance to bacteria, fungi, viruses and parasites, and influencing the host …

Fast bacterial growth reduces antibiotic accumulation and efficacy

U Łapińska, M Voliotis, KK Lee, A Campey, MRL Stone… - Elife, 2022 - elifesciences.org
Phenotypic variations between individual microbial cells play a key role in the resistance of
microbial pathogens to pharmacotherapies. Nevertheless, little is known about cell …

Antimicrobial peptides: the promising therapeutics for cutaneous wound healing

F Miao, Y Li, Z Tai, Y Zhang, Y Gao… - Macromolecular …, 2021 - Wiley Online Library
Chronic wound infections have caused an increasing number of deaths and economic
burden, which necessitates wound treatment options. Hitherto, the development of functional …

Marine invertebrate antimicrobial peptides and their potential as novel peptide antibiotics

SV Guryanova, SV Balandin… - Marine drugs, 2023 - mdpi.com
Marine invertebrates constantly interact with a wide range of microorganisms in their aquatic
environment and possess an effective defense system that has enabled their existence for …