Crystal growth with macromolecular additives

AG Shtukenberg, MD Ward, B Kahr - Chemical reviews, 2017 - ACS Publications
Interactions of macromolecules with growing crystalline surfaces play an important role in
biomineralization, determine survival of some organisms at low temperatures, and offer a …

Disrupting crystal growth through molecular recognition: designer therapies for kidney stone prevention

AG Shtukenberg, L Hu, A Sahota, B Kahr… - Accounts of chemical …, 2022 - ACS Publications
Conspectus Aberrant crystallization within the human body can lead to several disease
states or adverse outcomes, yet much remains to be understood about the critical stages …

Tautomerism unveils a self-inhibition mechanism of crystallization

W Tang, T Yang, CA Morales-Rivera, X Geng… - Nature …, 2023 - nature.com
Modifiers are commonly used in natural, biological, and synthetic crystallization to tailor the
growth of diverse materials. Here, we identify tautomers as a new class of modifiers where …

Molecular modifiers reveal a mechanism of pathological crystal growth inhibition

J Chung, I Granja, MG Taylor, G Mpourmpakis… - Nature, 2016 - nature.com
Crystalline materials are crucial to the function of living organisms, in the shells of molluscs,,,
the matrix of bone, the teeth of sea urchins, and the exoskeletons of coccoliths. However …

Dislocations in SrTiO3: Easy To Reduce but Not so Fast for Oxygen Transport

D Marrocchelli, L Sun, B Yildiz - Journal of the American Chemical …, 2015 - ACS Publications
The effect of dislocations on the chemical, electrical and transport properties in oxide
materials is important for electrochemical devices, such as fuel cells and resistive switches …

Engineering crystal modifiers: bridging classical and nonclassical crystallization

KN Olafson, R Li, BG Alamani, JD Rimer - Chemistry of Materials, 2016 - ACS Publications
The use of growth modifiers in natural, biological, and synthetic crystallization is a ubiquitous
strategy for controlling growth and achieving desired physicochemical properties. For …

Molecular imposters functioning as versatile growth modifiers of urate crystallization

W Tang, C Smith, CB Parry, J Meegan… - Crystal Growth & …, 2023 - ACS Publications
Interactions between molecular modifiers and crystal surfaces govern numerous processes
and structural outcomes of natural, biological, and synthetic crystallization. An efficient …

Antimalarials inhibit hematin crystallization by unique drug–surface site interactions

KN Olafson, TQ Nguyen, JD Rimer… - Proceedings of the …, 2017 - National Acad Sciences
In malaria pathophysiology, divergent hypotheses on the inhibition of hematin crystallization
posit that drugs act either by the sequestration of soluble hematin or their interaction with …

Boosting inhibition performance of natural polyphenols for the prevention of calcium oxalate kidney stones through synergistic cooperativity

S Li, D Zhou, Z Zhu, X Tan, W Tang… - Communications materials, 2023 - nature.com
Binary drug combination usually targets different pathways to achieve cooperative therapy,
but the exploitation of synergistic cooperativity between crystal growth modifiers that bind to …

Antagonistic cooperativity between crystal growth modifiers

W Ma, JF Lutsko, JD Rimer, PG Vekilov - Nature, 2020 - nature.com
Ubiquitous processes in nature and the industry exploit crystallization from multicomponent
environments,,,–; however, laboratory efforts have focused on the crystallization of pure …