As one of the significant challenges to human health, cancer has long been a focal point in
medical treatment. With ongoing advancements in the field of medicine, numerous …

Viruses can be designed to be tools and carrier vehicles for intratumoural immunotherapy.
Their nanometre-scale size and shape allow for functionalization with or encapsulation of …

Breast cancer's immunosuppressive environment hinders effective immunotherapy, but
oncolytic viruses hold promise for addressing this challenge by targeting tumor cells and …

Pancreatic cancer presents formidable challenges due to rapid progression and resistance
to conventional treatments. Oncolytic viruses (OVs) selectively infect cancer cells and cause …

Gliomas are the most prevalent and devastating primary malignant brain tumors in adults.
Despite substantial advances in understanding glioma biology, there have been no …

Gliomas are the most prevalent and devastating primary malignant brain tumors in adults.
Despite substantial advances in understanding glioma biology, there have been no …

Glioma is a diverse category of tumors originating from glial cells encompasses various
subtypes, based on the specific type of glial cells involved. The most aggressive is …

Sindbis alphavirus vectors offer a promising platform for cancer therapy, serving as valuable
models for alphavirus-based treatment. This review emphasizes key studies that support the …

Oncolytic viruses (OVs) have emerged as a potential strategy for tumor treatment due to their
ability to selectively replicate in tumor cells, induce apoptosis, and stimulate immune …

Background A limitation of approved oncolytic viruses is their requirement for intratumoral (it)
injection. TILT-123 (igrelimogene litadenorepvec, Ad5/3-E2F-D24-hTNFα-IRES-hIL-2) is a …