Advances in the diagnosis and management of well-differentiated neuroendocrine neoplasms
Neuroendocrine neoplasms constitute a diverse group of tumors that derive from the
sensory and secretory neuroendocrine cells and predominantly arise within the pulmonary …
sensory and secretory neuroendocrine cells and predominantly arise within the pulmonary …
Electrophysiology of the pancreatic β-cell
FM Ashcroft, P Rorsman - Progress in biophysics and molecular biology, 1989 - Elsevier
1. A TP-Regulated K+-Channels (KA TP Channels)(a) Single-channel conductance and
voltage dependence (b) Permeability and selectivity (c) Kinetics (d) Effects of. 4 TP (i) …
voltage dependence (b) Permeability and selectivity (c) Kinetics (d) Effects of. 4 TP (i) …
A multi-signal fluorescent probe for simultaneously distinguishing and sequentially sensing cysteine/homocysteine, glutathione, and hydrogen sulfide in living cells
L He, X Yang, K Xu, X Kong, W Lin - Chemical Science, 2017 - pubs.rsc.org
Biothiols, which have a close network of generation and metabolic pathways among them,
are essential reactive sulfur species (RSS) in the cells and play vital roles in human …
are essential reactive sulfur species (RSS) in the cells and play vital roles in human …
Reconstitution of IKATP: An Inward Rectifier Subunit Plus the Sulfonylurea Receptor
N Inagaki, T Gonoi, JP Clement IV, N Namba… - Science, 1995 - science.org
A member of the inwardly rectifying potassium channel family was cloned here. The
channel, called BIR (Kir6. 2), was expressed in large amounts in rat pancreatic islets and …
channel, called BIR (Kir6. 2), was expressed in large amounts in rat pancreatic islets and …
Cardioprotective Effect of Diazoxide and Its Interaction With Mitochondrial ATP-Sensitive K+ Channels: Possible Mechanism of Cardioprotection
KD Garlid, P Paucek, V Yarov-Yarovoy… - Circulation …, 1997 - Am Heart Assoc
Previous studies showed a poor correlation between sarcolemmal K+ currents and
cardioprotection for ATP-sensitive K+ channel (KATP) openers. Diazoxide is a weak cardiac …
cardioprotection for ATP-sensitive K+ channel (KATP) openers. Diazoxide is a weak cardiac …
ATP-sensitive and inwardly rectifying potassium channels in smooth muscle
JM Quayle, MT Nelson… - Physiological reviews, 1997 - journals.physiology.org
The properties and roles of ATP-sensitive (KATP) and inwardly rectifying (KIR) potassium
channels are reviewed. Potassium channels regulate the membrane potential of smooth …
channels are reviewed. Potassium channels regulate the membrane potential of smooth …
Activation of KATP channels by H2S in rat insulin‐secreting cells and the underlying mechanisms
H2S is an important gasotransmitter, generated in mammalian cells from l‐cysteine
metabolism. As it stimulates KATP channels in vascular smooth muscle cells, H2S may also …
metabolism. As it stimulates KATP channels in vascular smooth muscle cells, H2S may also …
[HTML][HTML] Potassium channels in behavioral brain disorders. Molecular mechanisms and therapeutic potential: a narrative review.
Abstract Potassium channels (K+-channels) selectively control the passive flow of potassium
ions across biological membranes and thereby also regulate membrane excitability. Genetic …
ions across biological membranes and thereby also regulate membrane excitability. Genetic …
[HTML][HTML] Physiological and pathophysiological roles of ATP-sensitive K+ channels
S Seino, T Miki - Progress in biophysics and molecular biology, 2003 - Elsevier
ATP-sensitive potassium (KATP) channels are present in many tissues, including pancreatic
islet cells, heart, skeletal muscle, vascular smooth muscle, and brain, in which they couple …
islet cells, heart, skeletal muscle, vascular smooth muscle, and brain, in which they couple …
ATP-sensitive K+ channels and insulin secretion: their role in health and disease
FM Ashcroft, FM Gribble - Diabetologia, 1999 - search.proquest.com
Sulphonylureas have been used for over 50 years to enhance insulin secretion in patients
with Type II (non-insulin-dependent) diabetes mellitus but their therapeutic target was not …
with Type II (non-insulin-dependent) diabetes mellitus but their therapeutic target was not …