Current status and the epidemiology of malaria in the Middle East Region and beyond

M Al-Awadhi, S Ahmad, J Iqbal - Microorganisms, 2021 - mdpi.com
Vector-borne parasitic infectious diseases are important causes of morbidity and mortality
globally. Malaria is one of the most common vector-borne parasitic infection and is caused …

Prevalence of potential mediators of artemisinin resistance in African isolates of Plasmodium falciparum

A Owoloye, M Olufemi, ET Idowu, KM Oyebola - Malaria journal, 2021 - Springer
Background The devastating public health impact of malaria has prompted the need for
effective interventions. Malaria control gained traction after the introduction of artemisinin …

[PDF][PDF] Antimalarial flavonoid-glycoside from acacia pennata with inhibitory potential against PfDHFR-TS: an in-silico study

JH Zothantluanga, SK Aswin, M Rudrapal… - Biointerface Res. Appl …, 2021 - researchgate.net
Drug resistance, toxicity, and adverse effects of current antimalarial drugs have mandated
the need to search for newer antimalarial agents. The present study aims to identify …

Seasonal malaria chemoprevention in a context of high presumed sulfadoxine-pyrimethamine resistance: malaria morbidity and molecular drug resistance profiles in …

I Molina-De la Fuente, MJ Sagrado Benito, E Lasry… - Malaria Journal, 2023 - Springer
Background Seasonal malaria chemoprevention (SMC) using sulfadoxine-pyrimethamine
plus amodiaquine (SP-AQ), is a community-based malaria preventive strategy commonly …

Antimalarial drug efficacy and resistance in malaria‐endemic countries in HANMAT‐PIAM_net countries of the Eastern Mediterranean Region 2016–2020: Clinical …

M Adam, S Nahzat, Q Kakar, M Assada… - Tropical Medicine & …, 2023 - Wiley Online Library
Abstract Introduction The World Health Organization recommends regular monitoring of the
efficacy of nationally recommended antimalarial drugs. We present the results of studies on …

Prevalence of arps10, fd, pfmdr-2, pfcrt and pfkelch13 gene mutations in Plasmodium falciparum parasite population in Uganda

M Ocan, FK Ashaba, S Mwesigwa, K Edgar… - PLoS …, 2022 - journals.plos.org
In Uganda, Artemether-Lumefantrine and Artesunate are recommended for uncomplicated
and severe malaria respectively, but are currently threatened by parasite resistance. Genetic …

Bibliometric analysis of antimalarial drug resistance

J Zhang, M Shahbaz, M Ijaz, H Zhang - Frontiers in Cellular and …, 2024 - frontiersin.org
Background Malaria has always been a serious infectious disease prevalent in the world.
Antimalarial drugs such as chloroquine and artemisinin have been the main compounds …

Comparative analysis of targeted next-generation sequencing for Plasmodium falciparum drug resistance markers

C Kunasol, AM Dondorp, EM Batty, V Nakhonsri… - Scientific reports, 2022 - nature.com
Well-defined molecular resistance markers are available for a range of antimalarial drugs,
and molecular surveillance is increasingly important for monitoring antimalarial drug …

Molecular speciation of Plasmodium and multiplicity of P. falciparum infection in the Central region of Ghana

E Aninagyei, DM Puopelle, I Tukwarlba… - PLOS Global Public …, 2024 - journals.plos.org
Malaria is endemic in the Central region of Ghana, however, the ecological and the
seasonal variations of Plasmodium population structure and the intensity of malaria …

Targeted amplicon deep sequencing for monitoring antimalarial resistance markers in western Kenya

V Osoti, M Akinyi, K Wamae, KM Kimenyi… - Antimicrobial Agents …, 2022 - Am Soc Microbiol
Molecular surveillance of Plasmodium falciparum parasites is important to track emerging
and new mutations and trends in established mutations and should serve as an early …