[HTML][HTML] Alzheimer disease pathogenesis: insights from molecular and cellular biology studies of oligomeric Aβ and tau species

XQ Chen, WC Mobley - Frontiers in Neuroscience, 2019 - frontiersin.org
Alzheimer disease (AD) represents an oncoming epidemic that without an effective
treatment promises to exact extraordinary human and financial burdens. Studies of …

E2F4 as a single multifactorial target against Alzheimer's disease

N López-Sánchez, M Ramón-Landreau, C Trujillo… - bioRxiv, 2020 - biorxiv.org
Alzheimer's disease (AD) has a multifactorial etiology, which requires a single multi-target
approach for an efficient treatment. We have focused on E2F4, a transcription factor that …

[PDF][PDF] The interplay of epigenetics and metabolism in Alzheimer's disease

L Traxler - 2020 - marshallplan.at
Old age is the most significant risk factor for several diseases, including diabetes, cancer,
and a majority of dementias including Alzheimer's disease (AD). A dominating research …