Preclinical evidence has firmly established bidirectional interactions among the brain, the
gut, and the gut microbiome. Candidate signaling molecules and at least three …

The gut-brain axis plays an important role in maintaining homeostasis. Many intrinsic and
extrinsic factors influence signaling along this axis, modulating the function of both the …

The gut microbiome is associated with diverse diseases,–, but a universal signature of a
healthy or unhealthy microbiome has not been identified, and there is a need to understand …

Hosting millions of microorganisms, the digestive tract is the primary and most important part
of bacterial colonization. On one side, in cases of opportunistic invasion, the abundant …

Irritable bowel syndrome (IBS) remains one of the most common gastrointestinal disorders
seen by clinicians in both primary and secondary care. Since publication of the last British …

Gastrointestinal symptoms are highly prevalent, but many people who have them will have
no organic explanation for their symptoms. Most of these people will be labelled as having a …

Irritable bowel syndrome (IBS) is one of the most common disorders of gut–brain interaction
worldwide, defined according to patterns of gastrointestinal symptoms as described by the …

The human gut microbiota has now been associated with drug responses and efficacy, while
chemical compounds present in these drugs can also impact the gut bacteria. However …

The number of microbiome-related studies has notably increased the availability of data on
human microbiome composition and function. These studies provide the essential material …

The development of next-generation sequencing technology has enabled researchers to
explore and understand the gut microbiome from a broader and deeper perspective …