Polystyrene nanoplastics deteriorate LPS-modulated duodenal permeability and inflammation in mice via ROS drived-NF-κB/NLRP3 pathway
Y He, Z Li, T Xu, D Luo, Q Chi, Y Zhang, S Li - Chemosphere, 2022 - Elsevier
The widespread occurrence of nanoplastics (NPs), has markedly affected the ecosystem
and has become a global threat to animals and human health. There is growing evidence …
and has become a global threat to animals and human health. There is growing evidence …
Breaking the gingival barrier in periodontitis
L Vitkov, J Singh, C Schauer, B Minnich… - International Journal of …, 2023 - mdpi.com
The break of the epithelial barrier of gingiva has been a subject of minor interest, albeit
playing a key role in periodontal pathology, transitory bacteraemia, and subsequent …
playing a key role in periodontal pathology, transitory bacteraemia, and subsequent …
Gastrointestinal tract organoids as novel tools in drug discovery
L Zhou, D Luo, W Lu, J Han, M Zhao, X Li… - Frontiers in …, 2024 - frontiersin.org
Organoids, characterized by their high physiological attributes, effectively preserve the
genetic characteristics, physiological structure, and function of the simulated organs. Since …
genetic characteristics, physiological structure, and function of the simulated organs. Since …
[HTML][HTML] Possible role of the gut microbiome in mediating the beneficial effects of the six-herbal formulation STW 5-II on digestive health
RM Ammar, EM Pferschy-Wenzig, P Van den Abbeele… - Phytomedicine, 2023 - Elsevier
Background STW 5-II is a combination of six herbal extracts with clinically proven efficacy in
functional dyspepsia (FD) and irritable bowel syndrome (IBS). STW 5-II contains a wide …
functional dyspepsia (FD) and irritable bowel syndrome (IBS). STW 5-II contains a wide …
Rice bran extract mitigates depressive-like behavior in dextran sulfate sodium-induced colitis: Involvement of the gut-brain axis and Sirt1 signaling pathway
HM Shendy, SS Mohamed, EA Abd El-Haleim… - Food and Chemical …, 2024 - Elsevier
Inflammatory bowel disease (IBD) patients frequently suffer from depressive disorders as
well. The present study was carried out to explore whether treatment with a standardized …
well. The present study was carried out to explore whether treatment with a standardized …
Naphthoquinone derivatives as P-glycoprotein inducers in inflammatory bowel disease: 2D monolayers, 3D spheroids, and in vivo models
N Mahmoud, MEF Hegazy, W Wadie… - Pharmacological …, 2022 - Elsevier
Inflammatory bowel disease (IBD) represents a chronic inflammation of the gastrointestinal
tract characterized by an overreaction of immune responses and damage at the intestinal …
tract characterized by an overreaction of immune responses and damage at the intestinal …
Thymus serpyllum Exhibits Anti-Diabetic Potential in Streptozotocin-Induced Diabetes Mellitus Type 2 Mice: A Combined Biochemical and In Vivo Study
J Azhar, P John, A Bhatti - Nutrients, 2022 - mdpi.com
Type 2 diabetes mellitus (T2DM) is a complex metabolic disorder that is characterized by
hyperglycemia, insulin resistance, and lack of insulin production. It has been previously …
hyperglycemia, insulin resistance, and lack of insulin production. It has been previously …
Selenium deficiency increased duodenal permeability and decreased expression of antimicrobial peptides by activating ROS/NF-κB signal pathway in chickens
H Yujiao, T Xinyu, F Xue, L Zhe, P Lin, S Guangliang… - Biometals, 2023 - Springer
Selenium (Se) is an essential trace element for the body. Various organs of the body,
including the intestine, are affected by its deficiency. Se deficiency can induce oxidative …
including the intestine, are affected by its deficiency. Se deficiency can induce oxidative …
Bacillus amyloliquefaciens SC06 Relieving Intestinal Inflammation by Modulating Intestinal Stem Cells Proliferation and Differentiation via AhR/STAT3 Pathway in …
Q Wang, F Wang, Y Zhou, X Li, S Xu… - Journal of Agricultural …, 2024 - ACS Publications
Bacillus amyloliquefaciens is a well-accepted probiotic, with many benefits for both humans
and animals. The ability of intestinal stem cells (ISCs) to develop into several intestinal …
and animals. The ability of intestinal stem cells (ISCs) to develop into several intestinal …
Anti-nociceptive effect of STW 5-II in rodent models of stress and post-inflammatory visceral hypersensitivity
E Noor-Mohammadi, T Yuan, CO Ligon, RM Ammar… - Phytomedicine, 2024 - Elsevier
Aims Visceral hypersensitivity is a therapy-resistant hallmark of irritable bowel syndrome
(IBS). Many IBS patients' symptoms develop following an acute colitis, and most report that …
(IBS). Many IBS patients' symptoms develop following an acute colitis, and most report that …