The power prior has been widely used in many applications covering a large number of
disciplines. The power prior is intended to be an informative prior constructed from historical …

The growth of biostatistics has been phenomenal in recent years and has been marked by
considerable technical innovation in both methodology and computational practicality. One …

Bayesian clinical trial designs offer the possibility of a substantially reduced sample size,
increased statistical power, and reductions in cost and ethical hazard. However when prior …

To assess water quality standards, measurements of water quality under the Clean Water
Act are collected on a regular basis over a period of time. The data are analyzed to evaluate …

Incorporating historical information into the design and analysis of a new clinical trial has
been the subject of much discussion as a way to increase the feasibility of trials in situations …

Information‐theoretic methodologies are increasingly being used in various disciplines.
Frequently an information measure is adapted for a problem, yet the perspective of …

Use of historical data and real‐world evidence holds great potential to improve the efficiency
of clinical trials. One major challenge is to effectively borrow information from historical data …

Mixture priors provide an intuitive way to incorporate historical data while accounting for
potential prior-data conflict by combining an informative prior with a noninformative prior …

The power prior has emerged as a useful informative prior for the incorporation of historical
data in a Bayesian analysis. Viewing hierarchical modeling as the" gold standard" for …

A biosimilar product refers to a follow-on biologic that is intended to be approved for
marketing on the basis of biosimilarity to an existing patented biological product (ie the …