[HTML][HTML] Nuclear magnetic resonance/single molecule fluorescence combinations to study dynamic protein systems
IM Vedel, A Papagiannoula, S Naudi-Fabra… - Current Opinion in …, 2023 - Elsevier
Many proteins require different structural states or conformations for function, and
intrinsically disordered proteins, ie proteins without stable three-dimensional structure, are …
intrinsically disordered proteins, ie proteins without stable three-dimensional structure, are …
The type III secretion system effector network hypothesis
J Sanchez-Garrido, D Ruano-Gallego… - Trends in …, 2022 - cell.com
Type III secretion system (T3SS) effectors are key virulence factors that underpin the
infection strategy of many clinically important Gram-negative pathogens, including …
infection strategy of many clinically important Gram-negative pathogens, including …
[HTML][HTML] Speaking the host language: how Salmonella effector proteins manipulate the host
TD Pillay, SU Hettiarachchi, J Gan… - …, 2023 - microbiologyresearch.org
Salmonella injects over 40 virulence factors, termed effectors, into host cells to subvert
diverse host cellular processes. Of these 40 Salmonella effectors, at least 25 have been …
diverse host cellular processes. Of these 40 Salmonella effectors, at least 25 have been …
Host manipulation by bacterial type III and type IV secretion system effector proteases
Proteases are powerful enzymes, which cleave peptide bonds, leading most of the time to
irreversible fragmentation or degradation of their substrates. Therefore they control many …
irreversible fragmentation or degradation of their substrates. Therefore they control many …
[HTML][HTML] Manipulation of host immune defenses by effector proteins delivered from multiple secretion systems of Salmonella and its application in vaccine research
G Zhou, Y Zhao, Q Ma, Q Li, S Wang, H Shi - Frontiers in Immunology, 2023 - frontiersin.org
Salmonella is an important zoonotic bacterial species and hazardous for the health of
human beings and livestock globally. Depending on the host, Salmonella can cause …
human beings and livestock globally. Depending on the host, Salmonella can cause …
Development of a genomics-based approach to identify putative hypervirulent nontyphoidal Salmonella isolates: Salmonella enterica Serovar Saintpaul as a model
While differences in human virulence have been reported across nontyphoidal Salmonella
(NTS) serovars and associated subtypes, a rational and scalable approach to identify …
(NTS) serovars and associated subtypes, a rational and scalable approach to identify …
[HTML][HTML] Control of host PTMs by intracellular bacteria: An opportunity toward novel anti-infective agents
V Stevenin, J Neefjes - Cell chemical biology, 2022 - cell.com
Intracellular bacteria have developed a multitude of mechanisms to influence the post-
translational modifications (PTMs) of host proteins to pathogen advantages. The recent …
translational modifications (PTMs) of host proteins to pathogen advantages. The recent …
SopD from Salmonella specifically inactivates Rab8
S Savitskiy, A Itzen - Biochimica et Biophysica Acta (BBA)-Proteins and …, 2021 - Elsevier
Salmonella outer protein D (SopD) is secreted into a host during the first stages of the
Salmonella infection and contributes to the systemic virulence of the bacterium. SopD2 is a …
Salmonella infection and contributes to the systemic virulence of the bacterium. SopD2 is a …
[HTML][HTML] Shift in vacuolar to cytosolic regime of infecting Salmonella from a dual proteome perspective
By applying dual proteome profiling to Salmonella enterica serovar Typhimurium (S.
Typhimurium) encounters with its epithelial host (here, S. Typhimurium infected human …
Typhimurium) encounters with its epithelial host (here, S. Typhimurium infected human …
Structural biology of the invasion arsenal of Gram‐negative bacterial pathogens
In the last several years, there has been a tremendous progress in the understanding of host–
pathogen interactions and the mechanisms by which bacterial pathogens modulate …
pathogen interactions and the mechanisms by which bacterial pathogens modulate …