The pH‐responsive theragnostics exhibit great potential for precision diagnosis and
treatment of diseases. Herein, acidity‐activatable nanoparticles of GB@ P based on glucose …

Prophylactic vaccination strategies designed to prevent diseases caused by pathogens
using the phagolysosome of innate immune cells as a site of intracellular replication and …

Cryptococcus neoformans, an opportunistic yeast pathogen, relies on a complex network of
stress response pathways that allow for proliferation in the host. In Saccharomyces …

The importance of fungal infections, particularly those caused by yeasts, is increasing
among the medical community. Candida albicans and Cryptococcus neoformans are …

Fungal pathogens present a growing threat to both humans and global health security alike.
Increasing evidence of antifungal resistance in fungal populations that infect both humans …

Nitric oxide (NO), a highly reactive free radical generated endogenously by nitric oxide
synthase (NOS), plays crucial roles in immune defense against a broad range of pathogens …

Trehalose-6-phosphate synthase (TPS1) was identified as a virulence factor for
Cryptococcus neoformans and a promising therapeutic target. This study reveals previously …

Cryptococcal meningoencephalitis (CM), caused by the fungal pathogen Cryptococcus
neoformans species complex, can lead to high mortality or severe neurological sequelae in …

Cryptococcosis is a fungal infection caused by members of the genus Cryptococcus.
Worldwide, the most prevalent pathogen of this genus is the encapsulated saprophyte …