For many patients with terminal/advanced cardiac failure, heart transplantation is the most
effective, durable treatment option, and offers the best prospects for a high quality of life. The …

COVID‐19 is characterized by dysregulated immune responses, metabolic dysfunction and
adverse effects on the function of multiple organs. To understand host responses to COVID …

To address the ongoing shortage of organs available for replacement, xenotransplantation
of hearts, corneas, skin, and kidneys has been attempted. However, a major obstacle facing …

MicroRNAs are small, noncoding molecules of about twenty-two nucleotides with crucial
roles in both healthy and pathological cells. Their expression depends not only on genetic …

Fetal alcohol spectrum disorders (FASD) are difficult to diagnose since many heavily
exposed infants, at risk for intellectual disability, do not exhibit craniofacial dysmorphology or …

The recent pig heart transplant in a patient at the University of Maryland Medical Center has
stimulated renewed interest in the xenotransplantation of organs from genetically …

Ovarian cancer (OC) is the third most common gynecological malignancy with the highest
mortality worldwide. OC is usually diagnosed at an advanced stage, and the standard …

Objective Stimulant use instigates abstinence syndrome in humans. miRNAs are a critical
component for the pathophysiology of stimulant abstinence. Here we sought to identify a …

The control of gene expression by microRNAs (miRNAs, miR) influences many cellular
functions, including cellular differentiation, cell proliferation, cell development, and functional …

The human leukocyte antigen G1 (HLA-G1), a non-classical class I major histocompatibility
complex (MHC-I) protein, is a potent immunomodulatory molecule at the maternal/fetal …