Periodontitis involves the loss of connective tissue attachment and alveolar bone. Single cell
RNA-seq experiments have provided new insight into how resident cells and infiltrating …

Sonic hedgehog (Shh) is a secreted protein with important roles in mammalian
embryogenesis. During tooth development, Shh is primarily expressed in the dental …

Craniofacial development involves several complex tissue movements including several
fusion processes to form the frontonasal and maxillary structures, including the upper lip and …

Background Cannabinoids including cannabidiol have recognized genotoxic activities but
their significance has not been studied broadly epidemiologically across the teratological …

Sonic hedgehog (Shh) plays important roles in developmental of vertebrate animal central
nervous system (CNS), and Gli is its downstream signal molecule. Shh signalling is …

Head and neck squamous cell carcinoma (HNSCC) is the sixth leading malignancy
worldwide, with a poor prognosis and limited treatment options. Molecularly targeted …

Myopia has become one of the most critical health problems in the world with the increasing
time spent indoors and increasing close work. Pathological myopia may have multiple …

Hedgehog (Hh) signaling is a classic morphogen in controlling embryonic development and
tissue repairing. Aberrant activation of Hh signaling has been well documented in liver …

Early life stages of fish are highly sensitive to crude oil exposure and thus, short term
exposures during critical developmental periods could have detrimental consequences for …

Three distinct hedgehog (HH) molecules,(sonic, desert, and indian), two HH receptors
(PTCH1 and PTCH2), a membrane bound activator (SMO), and downstream three …