Mood disorders are associated with elevated inflammation, and the reduction of symptoms
after multiple treatments is often accompanied by pro-inflammation restoration. A variety of …

Despite decades of intensive research, the biological mechanisms that causally underlie
depression are still unclear, and therefore the development of novel effective antidepressant …

Data from clinical and preclinical studies indicate that immune dysregulation, specifically of
inflammatory processes, is associated with symptoms of major depressive disorder (MDD) …

Major depressive disorder (MDD) will affect one out of every five people in their lifetime and
is the leading cause of disability worldwide. Nevertheless, mechanisms associated with the …

The limited success in understanding the pathophysiology of major depression may result
from excessive focus on the dysfunctioning of neurons, as compared with other types of …

Although deep brain stimulation (DBS) is an established treatment choice for Parkinson's
disease (PD), essential tremor and movement disorders, its effectiveness for the …

Major depressive disorder is a severe, disabling disorder that affects around 4.7% of the
population worldwide. Based on the monoaminergic hypothesis of depression, monoamine …

Short-and long-term antidepressant effects of deep brain stimulation (DBS) in treatment-
resistant depression (TRD) have been demonstrated for several brain targets in open-label …

Major depressive disorder (MDD) is a common psychiatric disorder effecting approximately
121 million people worldwide and recent reports from the World Health Organization (WHO) …

Abstract Treatment resistance in alcohol use disorders (AUD) is a major problem for affected
individuals and for society. In the search of new treatment options, few case studies using …