In the past decade, multicomponent reactions have experienced a renaissance as powerful
peptide macrocyclization tools enabling the rapid creation of skeletal complexity and …

Molecules | Free Full-Text | Synthetic Approaches and Pharmacological Activity of 1,3,4-Oxadiazoles:
A Review of the Literature from 2000–2012 Next Article in Journal Chemical Composition of …

Synthetic methods that provide control over macrocycle conformation and, at the same time,
mitigate the polarity of peptide bonds represent valuable tools for the discovery of new …

Passerini reaction involving an oxo component, an isocyanide, and a nucleophile in a single
step to prepare α-acyloxy carboxamide, was first discovered by Passerini about 90 years …

A novel magnetic iron oxide supported phenylsulfonic acid (Fe 3 O 4@ Ph-SO 3 H) with core-
shell structure is prepared, characterized and applied as efficient nanocatalyst for green …

Triphenylphosphine (TPP), dialkyl acetylenedicarboxylates (DAAD), and acids such as
phenols, imides, amides, enols, oximes and alcohols react with each other via a …

Oxadiazole scaffold is one of the most important heterocyclic fragments, which is considered
as a perspective building block for drug discovery. Substituted 1, 3, 4-oxadiazoles had been …

An easy and convenient method is reported for the synthesis of polyhydroquinoline
derivatives in solvent-free conditions under microwave irradiation in the presence of …

An efficient and straightforward synthesis of functionalized furo [3, 2-c] coumarins via a one-
pot oxidative pseudo three-component condensation of aldehydes and 4-hydroxycoumarin …

N-Isocyaniminotriphenylphosphorane (NIITP) is a functionalized isonitrile that has been
extensively applied in a variety of organic reactions during the last two decades. This …