Colorectal cancer genetics, incidence and risk factors: in search for targeted therapies

R Hull, FZ Francies, M Oyomno… - Cancer management and …, 2020 - Taylor & Francis
Each year, colorectal cancers (CRCs) affect over a quarter of a million people. The risk of
developing CRC in industrialized nations is approximately 5%. When the disease is …

Incidence and risk factors for colorectal cancer in Africa: a systematic review and meta-analysis

NN Tazinkeng, EF Pearlstein, M Manda-Mapalo… - BMC …, 2024 - Springer
Introduction Colorectal cancer (CRC) is the second leading cause of cancer-related death
worldwide. There is a significant burden of mortality from colorectal cancer in Africa. Due to …

Treatment of colorectal cancer in Sub‐Saharan Africa: Results from a prospective Nigerian hospital registry

A Sharma, OI Alatise, AO Adisa… - Journal of surgical …, 2020 - Wiley Online Library
Background Colorectal cancer (CRC) is the third most common cancer worldwide. Mortality
for CRC is improving in high income countries, but in low and middle income countries, rates …

Colorectal cancer in a patient with intestinal schistosomiasis: a case report from Kilimanjaro Christian Medical Center Northern Zone Tanzania

AM Herman, A Kishe, H Babu, H Shilanaiman… - World journal of surgical …, 2017 - Springer
Background Colorectal cancer associated with chronic intestinal schistosomiasis has been
linked with the chronic inflammation as a result of schistosomal ova deposition in the …

Prevalence and trends of drinking water disinfection byproducts-related cancers in Addis Ababa, Ethiopia

N Tafesse, M Porcelli, SR Gari… - Environmental Health …, 2022 - journals.sagepub.com
Background: Disinfection byproducts (DBPs) from chlorinated drinking water have been
linked to an increased risk of cancer in the bladder, stomach, colon, and rectum. No studies …

Diverging likelihood of colon and rectal cancer in Yogyakarta, Indonesia: A cross sectional study

H Puspitaningtyas, SH Hutajulu, J Fachiroh… - Plos one, 2024 - journals.plos.org
Objectives Colon and rectal cancer are associated with different risk factors and prognostic.
However, this discrepancy has not been widely explored in the local population. This study …

Colorectal cancer in northern Tanzania: increasing trends and late presentation present major challenges

AM Herman, AT Hawkins, K Misso, C Issangya… - JCO Global …, 2020 - ascopubs.org
PURPOSE A trend of increasing incidence of colorectal cancer (CRC) has been observed in
northern Tanzania. Studies have shown a six-fold increase in CRC in the past decade, with …

Pathological characteristics, prognostic determinants and the outcome of patients diagnosed with colorectal adenocarcinoma at the University Teaching Hospital of …

D Uwamariya, D Ruhangaza… - Canadian Journal of …, 2022 - Wiley Online Library
Worldwide, colorectal cancer (CRC) is the second most diagnosed cancer in female and the
third in men, arising from the epithelium of the colorectum. It is known that colorectal cancer …

Frequency of KRAS and BRAF mutations in colorectal carcinoma and their association with clinical-pathological characteristics in a tertiary hospital in Kenya

S Gakinya, A Njau, A Abdallah, A Nzioka… - Frontiers in …, 2024 - frontiersin.org
Introduction Colorectal carcinoma is a leading cause of cancer morbidity and mortality
globally. Its management includes the use of targeted therapy which require assessment for …

Colorectal adenocarcinoma in East Africa: a narrative literature review

R Wismayer - Journal of Advances in Medicine and …, 2020 - publications.journalstm.com
This paper is a review of work done on colorectal adenocarcinoma in East Africa showing
geographic spread, age and sex ratios, clinical presentation, management and predominant …