The ageing process is a systemic decline from cellular dysfunction to organ degeneration,
with more predisposition to deteriorated disorders. Rejuvenation refers to giving aged cells …

With the advent of population aging, aging-related diseases have become a challenge for
governments worldwide. Sarcopenia has defined as a clinical syndrome associated with …

Regulation of glial activation and neuroinflammation are critical factors in the pathogenesis
of Alzheimer's disease (AD). YKL-40, a primarily astrocytic protein encoded by the gene …

Neurodegenerative diseases encompass a large group of conditions that are clinically and
pathologically diverse yet are linked by a shared pathology of misfolded proteins. The …

The association of age with a higher vulnerability to COVID-19 infection is a subject of major
importance. Several factors, including higher stress due to social isolation, diminished …

Type 2 diabetes mellitus (T2DM) patients are at a higher risk of developing Alzheimer's
disease (AD). Mounting evidence suggests the emerging important role of circadian rhythms …

Aims Over the past years, interest in chrono-nutrition has grown enormously as the
fundamental role of circadian rhythms in regulating most physiological and metabolic …

Throughout the course of life, there are age-related changes in sleep. Despite these normal
changes, there is a high percentage of older adults that report sleep dissatisfaction with a …

Aging, in a large measure, has long been defined as the resultant of oxidative stress acting
on the cells. The cellular machinery eventually malfunctions at the basic level by the …

Dysfunction of circadian and sleep rhythms is an early feature of many neurodegenerative
diseases. Alzheimer's disease (AD) is a progressive neurodegenerative disorder resulting in …