Endometriosis: epidemiology, diagnosis and clinical management

P Parasar, P Ozcan, KL Terry - Current obstetrics and gynecology reports, 2017 - Springer
Abstract Purpose of Review Endometriosis is a disease of adolescents and reproductive-
aged women characterized by the presence of endometrial tissue outside the uterine cavity …

Progesterone resistance in endometriosis: current evidence and putative mechanisms

P Zhang, G Wang - International Journal of Molecular Sciences, 2023 - mdpi.com
Endometriosis is an estrogen-dependent disease characterized by the growth of
endometrial-like tissue outside the uterus. Progestins are currently the most commonly used …

[HTML][HTML] Endometriosis: where are we and where are we going?

AD Greene, SA Lang, JA Kendziorski… - Reproduction …, 2016 - ncbi.nlm.nih.gov
Endometriosis currently affects∼ 5.5 million reproductive-aged women in the US with
symptoms such as painful periods (dysmenorrhea), chronic pelvic pain, pain with …

GnRH and GnRH receptors in the pathophysiology of the human female reproductive system

R Maggi, AM Cariboni, MM Marelli… - Human reproduction …, 2016 - academic.oup.com
BACKGROUND Human reproduction depends on an intact hypothalamic–pituitary–gonadal
(HPG) axis. Hypothalamic gonadotrophin-releasing hormone (GnRH) has been recognized …

Oral contraceptives for pain associated with endometriosis

J Brown, TJ Crawford, S Datta… - Cochrane Database of …, 2018 - cochranelibrary.com
Background Endometriosis is a common gynaecological condition which affects many
women of reproductive age worldwide and is a major cause of pain and infertility. The …

Current updates on the role of microbiome in endometriosis: a narrative review

HL Ser, SJ Au Yong, MN Shafiee, NM Mokhtar, RAR Ali - Microorganisms, 2023 - mdpi.com
Endometriosis affects approximately 6 to 10% of reproductive-age women globally. Despite
much effort invested, the pathogenesis that promotes the development, as well as the …

Minimally invasive treatment of adenomyosis

M Dueholm - Best Practice & Research Clinical Obstetrics & …, 2018 - Elsevier
The aim of the present review is to give a comprehensive overview of minimal invasive
treatment options and suggest a minimally invasive approach in women with adenomyosis …

[HTML][HTML] Control of endometriosis-associated pain with etonogestrel-releasing contraceptive implant and 52-mg levonorgestrel-releasing intrauterine system …

N Carvalho, D Margatho, K Cursino, CL Benetti-Pinto… - Fertility and sterility, 2018 - Elsevier
Objective To assess the efficacy of an etonogestrel (ENG)-releasing contraceptive implant or
the 52-mg levonorgestrel-releasing intrauterine system (LNG-IUS) in the control of …

Flavonoids quercetin and kaempferol are NR4A1 antagonists and suppress endometriosis in female mice

L Zhang, K Mohankumar, G Martin, F Mariyam… - …, 2023 - academic.oup.com
Abstract Nuclear receptor 4A1 (NR4A1) plays an important role in endometriosis
progression; levels of NR4A1 in endometriotic lesions are higher than in normal …

Role of SIRT1 and progesterone resistance in normal and abnormal endometrium

TH Kim, SL Young, T Sasaki, JL Deaton… - The Journal of …, 2022 - academic.oup.com
Context Progesterone resistance, a known pathologic condition associated with a reduced
cellular response to progesterone and heightened estrogen responses, appears to have a …