Acute-phase proteins: As diagnostic tool

S Jain, V Gautam, S Naseem - Journal of pharmacy and bioallied …, 2011 - journals.lww.com
The varied reactions of the host to infection, inflammation, or trauma are collectively known
as the acute-phase response and encompass a wide range of pathophysiological …

Early detection of lung cancer biomarkers through biosensor technology: A review

A Roointan, TA Mir, SI Wani, KK Hussain… - … of pharmaceutical and …, 2019 - Elsevier
Lung cancer is undoubtedly one of the most serious health issues of the 21 st century. It is
the second leading cause of cancer-related deaths in both men and women worldwide …

Human body fluid proteome analysis

S Hu, JA Loo, DT Wong - Proteomics, 2006 - Wiley Online Library
The focus of this article is to review the recent advances in proteome analysis of human
body fluids, including plasma/serum, urine, cerebrospinal fluid, saliva, bronchoalveolar …

The MALDI-TOF mass spectrometric view of the plasma proteome and peptidome

GL Hortin - Clinical chemistry, 2006 - academic.oup.com
Background: Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry
(MALDI-TOF MS) and the related technique, surface-enhanced laser desorption/ionization …

Serum amyloid A: an acute-phase protein involved in tumour pathogenesis

E Malle, S Sodin-Semrl, A Kovacevic - Cellular and molecular life sciences, 2009 - Springer
The synthesis of acute-phase protein serum amyloid A (SAA) is largely regulated by
inflammation-associated cytokines and a high concentration of circulating SAA may …

Application of machine learning to proteomics data: classification and biomarker identification in postgenomics biology

AL Swan, A Mobasheri, D Allaway… - Omics: a journal of …, 2013 - liebertpub.com
Mass spectrometry is an analytical technique for the characterization of biological samples
and is increasingly used in omics studies because of its targeted, nontargeted, and high …

Identification of serum biomarkers for colon cancer by proteomic analysis

DG Ward, N Suggett, Y Cheng, W Wei… - British journal of …, 2006 - nature.com
Colorectal cancer (CRC) is often diagnosed at a late stage with concomitant poor prognosis.
Early detection greatly improves prognosis; however, the invasive, unpleasant and …

Sample preparation for serum/plasma profiling and biomarker identification by mass spectrometry

JL Luque-Garcia, TA Neubert - Journal of Chromatography A, 2007 - Elsevier
In this article, we present an overview of the different strategies for sample preparation for
identification by mass spectrometry (MS) of biomarkers from serum and/or plasma. We …

Clinical proteomics: searching for better tumour markers with SELDI-TOF mass spectrometry

JYMN Engwegen, MCW Gast, JHM Schellens… - Trends in …, 2006 - cell.com
Recently, the focus of cancer research has expanded from genetic information in the human
genome to protein expression analyses. Because this 'proteome'reflects the state of a cell …

iTRAQ identification of candidate serum biomarkers associated with metastatic progression of human prostate cancer

I Rehman, CA Evans, A Glen, SS Cross, CL Eaton… - PloS one, 2012 - journals.plos.org
A major challenge in the management of patients with prostate cancer is identifying those
individuals at risk of developing metastatic disease, as in most cases the disease will remain …