Clinical and experimental insight into pathophysiology, comorbidity and therapy of absence seizures
Absence seizures in children and teenagers are generally considered relatively benign
because of their non-convulsive nature and the large incidence of remittance in early …
because of their non-convulsive nature and the large incidence of remittance in early …
Large scale brain models of epilepsy: dynamics meets connectomics
MP Richardson - Journal of Neurology, Neurosurgery & Psychiatry, 2012 - jnnp.bmj.com
The brain is in a constant state of dynamic change, for example switching between cognitive
and behavioural tasks, and between wakefulness and sleep. The brains of people with …
and behavioural tasks, and between wakefulness and sleep. The brains of people with …
Altered functional–structural coupling of large-scale brain networks in idiopathic generalized epilepsy
The human brain is a large-scale integrated network in the functional and structural domain.
Graph theoretical analysis provides a novel framework for analysing such complex …
Graph theoretical analysis provides a novel framework for analysing such complex …
Identifying neural drivers with functional MRI: an electrophysiological validation
O David, I Guillemain, S Saillet, S Reyt… - PLoS …, 2008 - journals.plos.org
Whether functional magnetic resonance imaging (fMRI) allows the identification of neural
drivers remains an open question of particular importance to refine physiological and …
drivers remains an open question of particular importance to refine physiological and …
Generalized epileptic discharges show thalamocortical activation and suspension of the default state of the brain
Our objective was to evaluate the brain regions showing increased and decreased
metabolism in patients at the time of generalized bursts of epileptic discharges in order to …
metabolism in patients at the time of generalized bursts of epileptic discharges in order to …
Frontal theta EEG activity correlates negatively with the default mode network in resting state
We used simultaneously recorded EEG and fMRI to investigate in which areas the BOLD
signal correlates with frontal theta power changes, while subjects were quietly lying resting …
signal correlates with frontal theta power changes, while subjects were quietly lying resting …
Cellular and network mechanisms of spike‐wave seizures
H Blumenfeld - Epilepsia, 2005 - Wiley Online Library
Spike‐wave seizures are often considered a relatively “pure” form of epilepsy, with a uniform
defect present in all patients and involvement of the whole brain homogenously. Here, we …
defect present in all patients and involvement of the whole brain homogenously. Here, we …
Cortical and subcortical networks in human secondarily generalized tonic–clonic seizures
Generalized tonic–clonic seizures are among the most dramatic physiological events in the
nervous system. The brain regions involved during partial seizures with secondary …
nervous system. The brain regions involved during partial seizures with secondary …
Network connectivity in epilepsy: resting state fMRI and EEG–fMRI contributions
M Centeno, DW Carmichael - Frontiers in neurology, 2014 - frontiersin.org
There is a growing body of evidence pointing toward large-scale networks underlying the
core phenomena in epilepsy, from seizure generation to cognitive dysfunction or response …
core phenomena in epilepsy, from seizure generation to cognitive dysfunction or response …
Dynamic time course of typical childhood absence seizures: EEG, behavior, and functional magnetic resonance imaging
X Bai, M Vestal, R Berman, M Negishi… - Journal of …, 2010 - Soc Neuroscience
Absence seizures are 5–10 s episodes of impaired consciousness accompanied by 3–4 Hz
generalized spike-and-wave discharge on electroencephalography (EEG). The time course …
generalized spike-and-wave discharge on electroencephalography (EEG). The time course …