A research agenda for ageing in China in the 21st century: focusing on basic and translational research, long-term care, policy and social networks

EF Fang, C Xie, JA Schenkel, C Wu, Q Long… - Ageing research …, 2020 - Elsevier
One of the key issues facing public healthcare is the global trend of an increasingly ageing
society which continues to present policy makers and caregivers with formidable healthcare …

Management of frailty: opportunities, challenges, and future directions

E Dent, FC Martin, H Bergman, J Woo… - The Lancet, 2019 - thelancet.com
Frailty is a complex age-related clinical condition characterised by a decline in physiological
capacity across several organ systems, with a resultant increased susceptibility to stressors …

2021 update to the 2017 ACC expert consensus decision pathway for optimization of heart failure treatment: answers to 10 pivotal issues about heart failure with …

TM Maddox, JL Januzzi Jr, LA Allen, K Breathett… - Journal of the American …, 2021 - jacc.org
Abstract The 2017 ACC Expert Consensus Decision Pathway for Optimization of Heart
Failure Treatment was created to provide a practical, streamlined resource for clinicians …

[HTML][HTML] Physical rehabilitation for older patients hospitalized for heart failure

DW Kitzman, DJ Whellan, P Duncan… - … England Journal of …, 2021 - Mass Medical Soc
Background Older patients who are hospitalized for acute decompensated heart failure have
high rates of physical frailty, poor quality of life, delayed recovery, and frequent …

Frailty is intertwined with heart failure: mechanisms, prevalence, prognosis, assessment, and management

A Pandey, D Kitzman, G Reeves - JACC: Heart Failure, 2019 - jacc.org
Frailty, a syndrome characterized by an exaggerated decline in function and reserve of
multiple physiological systems, is common in older patients with heart failure (HF) and is …

[HTML][HTML] Physical functional performance and prognosis in patients with heart failure: a systematic review and meta-analysis

IJ Fuentes-Abolafio, B Stubbs… - BMC cardiovascular …, 2020 - Springer
Abstract Background Patients with Heart Failure (HF) show impaired functional capacities
which have been related to their prognosis. Moreover, physical functional performance in …

Epidemiology and impact of frailty in patients with atrial fibrillation in Europe

M Proietti, GF Romiti, M Vitolo, SL Harrison… - Age and …, 2022 - academic.oup.com
Background Frailty is a medical syndrome characterised by reduced physiological reserve
and increased vulnerability to stressors. Data regarding the relationship between frailty and …

Heart failure promotes multimorbidity through innate immune memory

Y Nakayama, K Fujiu, T Oshima, J Matsuda… - Science …, 2024 - science.org
Patients with heart failure (HF) often experience repeated acute decompensation and
develop comorbidities such as chronic kidney disease and frailty syndrome. Although this …

Frailty status modifies the efficacy of exercise training among patients with chronic heart failure and reduced ejection fraction: an analysis from the HF-ACTION trial

A Pandey, MW Segar, S Singh, GR Reeves… - Circulation, 2022 - Am Heart Assoc
Background: Supervised aerobic exercise training (ET) is recommended for stable
outpatients with heart failure (HF) with reduced ejection fraction (HFrEF). Frailty, a syndrome …

Frailty and the risk of all‐cause mortality and hospitalization in chronic heart failure: a meta‐analysis

I Uchmanowicz, CS Lee, C Vitale, S Manulik… - ESC heart …, 2020 - Wiley Online Library
To estimate the risk of all‐cause mortality and hospitalization in frail patients with chronic
heart failure (HF), a systematic search and meta‐analysis was carried out to identify all …