A large number of clinical trials have shown stem cell therapy to be a promising therapeutic
approach for the treatment of cardiovascular diseases. Since the first transplantation into …

Despite significant therapeutic advances, the prognosis of patients with heart failure (HF)
remains poor, and current therapeutic approaches are palliative in the sense that they do not …

Given the rising prevalence of cardiovascular disease worldwide and the limited therapeutic
options for severe heart failure, novel technologies that harness the regenerative capacity of …

Cardiovascular diseases are known as one of major causes of morbidity and mortality
worldwide. Despite the many advancement in therapies are associated with cardiovascular …

Cardiogenesis within embryos or associated with heart repair requires stem cell
differentiation into energetically competent, contracting cardiomyocytes. While it is widely …

Objectives: We evaluated the ability of human embryonic stem cells (hESCs) and their
cardiomyocyte derivatives (hESC-CMs) to engraft and improve myocardial performance in …

The potential usefulness of human embryonic stem cells for therapy derives from their ability
to form any cell in the body. This potential has been used to justify intensive research …

Driven by enormous clinical need, myocardial tissue engineering has become a prime focus
of research within the field of tissue engineering. Myocardial tissue engineering combines …

Substantial evidence indicates that cell transplantation can improve function of the infarcted
heart. A surprisingly wide range of non-myogenic cell types improves ventricular function …

Regeneration of the myocardium by transplantation of cardiomyocytes is an emerging
therapeutic strategy. Human embryonic stem cells (HESC) form cardiomyocytes readily but …