Atherosclerotic disease, such as myocardial infarction and stroke, is the number one killer
worldwide. Atherosclerosis is considered to be caused by multiple factors, including genetic …

At least 468 individual genes have been manipulated by molecular methods to study their
effects on the initiation, promotion, and progression of atherosclerosis. Most clinicians and …

Background Conventional coronary artery disease risk factors might potentially explain at
least 90% of the attributable risk of coronary artery disease. To better understand the …

Background Atherosclerosis is thought to be a disease of modern human beings and related
to contemporary lifestyles. However, its prevalence before the modern era is unknown. We …

One of the earliest and best-recognized elements of atherosclerosis is its close relationship
with circulating LDL (low-density lipoprotein). There is convincing evidence that LDL …

Recent technological advancements have made a tremendous impact in the fields of
biological anthropology and archaeology. Although advancements in DNA analysis have …

Vitamin K-antagonists (VKA) are the most widely used anti-thrombotic drugs with substantial
efficacy in reducing risk of arterial and venous thrombosis. Several lines of evidence …

Atherosclerosis and its complications, such as myocardial infarction and stroke, are the
major causes of morbidity and mortality, and development of effective therapies for both …

Aging, the main risk factor for cardiovascular disease (CVD), is becoming progressively
more prevalent in our societies. A better understanding of how aging promotes CVD is …

The clinical manifestations of atherosclerosis are nowadays the main cause of death in
industrialized countries, but atherosclerotic disease was found in humans who lived …