FOLFIRINOX for locally advanced pancreatic cancer: a systematic review and patient-level meta-analysis

M Suker, BR Beumer, E Sadot, L Marthey… - The Lancet …, 2016 - thelancet.com
Background 35% of patients with pancreatic cancer have unresectable locally advanced
disease at diagnosis. Several studies have examined systemic chemotherapy with …

An update on treatment options for pancreatic adenocarcinoma

A Lambert, L Schwarz, I Borbath… - … in medical oncology, 2019 - journals.sagepub.com
Pancreatic cancer is one of the most lethal solid organ tumors. Due to the rising incidence,
late diagnosis, and limited treatment options, it is expected to be the second leading cause …

Locally advanced pancreatic cancer: neoadjuvant therapy with folfirinox results in resectability in 60% of the patients

T Hackert, M Sachsenmaier, U Hinz… - Annals of …, 2016 - journals.lww.com
Objective: For patients with locally advanced and unresectable pancreatic cancer (PDAC),
neodadjuvant treatment and consecutive surgical exploration have been studied during the …

Chemotherapy for pancreatic cancer

C Springfeld, D Jäger, MW Büchler, O Strobel… - La Presse Medicale, 2019 - Elsevier
Chemotherapy is an important part of multimodality pancreatic cancer treatment. After
curative resection, adjuvant chemotherapy can significantly improve disease free survival …

Importance of normalization of CA19-9 levels following neoadjuvant therapy in patients with localized pancreatic cancer

S Tsai, B George, D Wittmann, PS Ritch… - Annals of …, 2020 - journals.lww.com
Objective: Carbohydrate antigen 19-9 (CA19-9) is a prognostic marker for patients with
pancreatic cancer (PC), but its value as a treatment biomarker is unclear. Summary …

Nab-paclitaxel plus gemcitabine in patients with locally advanced pancreatic cancer (LAPACT): a multicentre, open-label phase 2 study

PA Philip, J Lacy, F Portales, A Sobrero… - The lancet …, 2020 - thelancet.com
Background Treatment options for patients with unresectable locally advanced pancreatic
cancer are scarce. Results from a subanalysis of the phase 3 MPACT trial in metastatic …

Stratified survival of resected and overall pancreatic cancer patients in Europe and the USA in the early twenty-first century: a large, international population-based …

L Huang, L Jansen, Y Balavarca, M Babaei… - BMC medicine, 2018 - Springer
Background The prognosis of pancreatic cancer (PaC) strongly varies across different
stages and age groups, which has unfortunately not been well recorded in the literature …

Preoperative therapy and pancreatoduodenectomy for pancreatic ductal adenocarcinoma: a 25-year single-institution experience

JM Cloyd, MHG Katz, L Prakash… - Journal of …, 2017 - Elsevier
Background The purpose of this study was to evaluate a single-institution experience with
delivery of preoperative therapy to patients with pancreatic ductal adenocarcinoma (PDAC) …

Vascular resection for pancreatic cancer: 2019 French recommendations based on a literature review from 2008 to 6-2019

JR Delpero, A Sauvanet - Frontiers in Oncology, 2020 - frontiersin.org
Introduction: Vascular resection remains a subject of debate in the management of
Pancreatic Ductal Adenocarcinoma (PDAC). These French recommendations were drafted …

Pancreatic cancer–the past, the present, and the future

R Andersson, C Haglund, H Seppänen… - Scandinavian journal of …, 2022 - Taylor & Francis
Background Pancreatic cancer has been and still is associated with a very poor prognosis.
This is due to a lack of major breakthroughs with respect to early diagnosis, prognostication …