Rhabdomyosarcoma
SX Skapek, A Ferrari, AA Gupta, PJ Lupo… - Nature reviews disease …, 2019 - nature.com
Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma in children and
represents a high-grade neoplasm of skeletal myoblast-like cells. Decades of clinical and …
represents a high-grade neoplasm of skeletal myoblast-like cells. Decades of clinical and …
Zebrafish patient avatars in cancer biology and precision cancer therapy
In precision oncology, two major strategies are being pursued for predicting clinically
relevant tumour behaviours, such as treatment response and emergence of drug resistance …
relevant tumour behaviours, such as treatment response and emergence of drug resistance …
Visualizing engrafted human cancer and therapy responses in immunodeficient zebrafish
Xenograft cell transplantation into immunodeficient mice has become the gold standard for
assessing pre-clinical efficacy of cancer drugs, yet direct visualization of single-cell …
assessing pre-clinical efficacy of cancer drugs, yet direct visualization of single-cell …
Current and future treatment strategies for rhabdomyosarcoma
Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma in children, and can be
subcategorized histologically and/or based on PAX-FOXO1 fusion gene status. Over the last …
subcategorized histologically and/or based on PAX-FOXO1 fusion gene status. Over the last …
Crosstalk between YAP/TAZ and Notch signaling
A Totaro, M Castellan, D Di Biagio, S Piccolo - Trends in cell biology, 2018 - cell.com
How the behavior of cells in living tissues is orchestrated according to tissue needs, size,
and developmental stage is still poorly understood. Advances in these directions are …
and developmental stage is still poorly understood. Advances in these directions are …
Benefits of zebrafish xenograft models in cancer research
X Chen, Y Li, T Yao, R Jia - Frontiers in Cell and Developmental …, 2021 - frontiersin.org
As a promising in vivo tool for cancer research, zebrafish have been widely applied in
various tumor studies. The zebrafish xenograft model is a low-cost, high-throughput tool for …
various tumor studies. The zebrafish xenograft model is a low-cost, high-throughput tool for …
Rhabdomyosarcoma: current therapy, challenges, and future approaches to treatment strategies
Simple Summary Rhabdomyosarcoma (RMS) is a rare pediatric sarcoma affecting skeletal
muscle in children and young adults. It is responsible for 3% of all childhood malignant …
muscle in children and young adults. It is responsible for 3% of all childhood malignant …
Signaling pathways in Rhabdomyosarcoma invasion and metastasis
Rhabdomyosarcoma (RMS) is an aggressive childhood mesenchymal tumor with two major
molecular and histopathologic subtypes: fusion-positive (FP) RMS, characterized by the …
molecular and histopathologic subtypes: fusion-positive (FP) RMS, characterized by the …
Insights into pediatric rhabdomyosarcoma research: Challenges and goals
Overall survival rates for pediatric patients with high‐risk or relapsed rhabdomyosarcoma
(RMS) have not improved significantly since the 1980s. Recent studies have identified a …
(RMS) have not improved significantly since the 1980s. Recent studies have identified a …
Interaction between SNAI2 and MYOD enhances oncogenesis and suppresses differentiation in Fusion Negative Rhabdomyosarcoma
S Pomella, P Sreenivas, BE Gryder, L Wang… - Nature …, 2021 - nature.com
Rhabdomyosarcoma (RMS) is an aggressive pediatric malignancy of the muscle, that
includes Fusion Positive (FP)-RMS harboring PAX3/7-FOXO1 and Fusion Negative (FN) …
includes Fusion Positive (FP)-RMS harboring PAX3/7-FOXO1 and Fusion Negative (FN) …