Heterogeneity and treatment landscape of ovarian carcinoma
AC Veneziani, E Gonzalez-Ochoa, H Alqaisi… - Nature Reviews …, 2023 - nature.com
Ovarian carcinoma is characterized by heterogeneity at the molecular, cellular and
anatomical levels, both spatially and temporally. This heterogeneity affects response to …
anatomical levels, both spatially and temporally. This heterogeneity affects response to …
Circulating tumor DNA as a biomarker for predicting progression-free survival and overall survival in patients with epithelial ovarian cancer: a systematic review and …
C Taliento, G Morciano, C Nero, W Froyman… - International Journal of …, 2024 - Elsevier
Abstract Objectives Circulating tumor DNA (ctDNA) is emerging as a potential prognostic
biomarker in multiple tumor types. However, despite the many studies available on small …
biomarker in multiple tumor types. However, despite the many studies available on small …
Current Applications and Challenges of Next-Generation Sequencing in Plasma Circulating Tumour DNA of Ovarian Cancer
R Roque, IP Ribeiro, M Figueiredo-Dias, C Gourley… - Biology, 2024 - mdpi.com
Simple Summary Circulating tumour DNA (ctDNA) corresponds to fragments of cancer
genetic material circulating in body fluids, such as blood. Its isolation and analysis have …
genetic material circulating in body fluids, such as blood. Its isolation and analysis have …
Prediction of Chemoresistance—How Preclinical Data Could Help to Modify Therapeutic Strategy in High-Grade Serous Ovarian Cancer
J Wilczyński, E Paradowska, J Wilczyńska… - Current …, 2023 - mdpi.com
High-grade serous ovarian cancer (HGSOC) is one of the most lethal tumors generally and
the most fatal cancer of the female genital tract. The approved standard therapy consists of …
the most fatal cancer of the female genital tract. The approved standard therapy consists of …
Exploring evolutionary trajectories in ovarian cancer patients by longitudinal analysis of ctDNA
O Kutz, S Drukewitz, A Krüger, D Aust… - Clinical Chemistry and …, 2024 - degruyter.com
Objectives We analysed whether temporal heterogeneity of ctDNA encodes evolutionary
patterns in ovarian cancer. Methods Targeted sequencing of 275 cancer-associated genes …
patterns in ovarian cancer. Methods Targeted sequencing of 275 cancer-associated genes …