Purpose Triple-negative breast cancer (TNBC) is a heterogeneous group of tumors
comprising various breast cancers simply defined by the absence of estrogen receptor …

The androgen receptor signaling axis plays an essential role in the development, function
and homeostasis of male urogenital structures including the prostate gland although the …

Little is known of the underlying biology of estrogen receptor-negative, progesterone
receptor-negative (ER (−)/PR (−)) breast cancer (BC), and few targeted therapies are …

There is emerging evidence that the balance between estrogen receptor-α (ERα) and
androgen receptor (AR) signaling is a critical determinant of growth in the normal and …

Although the androgen receptor (AR) is a known clinical target in prostate cancer, little is
known about its possible role in breast cancer. We have investigated the role of AR …

Background Breast cancer is a hormone-dependent tumor. Most breast cancer cells have an
androgen receptor (AR), but the clinical value of AR expression is unclear. Methods AR …

Progesterone and its metabolites promote the viability of neurons in the brain and spinal
cord. Their neuroprotective effects have been documented in different lesion models …

Background: Continued efforts to phase out bisphenol A (BPA) from consumer products
have been met with the challenges of finding safer alternatives. Objectives: This study aimed …

Androgen receptor (AR) is an attractive target in breast cancer because of its frequent
expression in all the molecular subtypes, especially in estrogen receptor (ER)-positive …

Salivary duct carcinoma (SDC), a rare malignancy, manifests remarkable morphologic and
biologic resemblance to high-grade mammary ductal carcinoma. We contend that, similar to …