Background: Sepsis is a deadly immunological disorder and its pathophysiology is still
poorly understood. We aimed to determine if specific pro-inflammatory and anti-inflammatory …

Fungi cause more than a billion skin infections, more than 100 million mucosal infections, 10
million serious allergies and more than a million deaths each year. Global mortality owing to …

In an attempt to treat cancer patients with ERBB2 overexpressing tumors, we developed a
chimeric antigen receptor (CAR) based on the widely used humanized monoclonal antibody …

Objective and design The serial or dynamic changes of cytokine levels in severely septic
patients, between shock and no shock, survivors and non-survivors are still unclear …

Host predisposition influences risk of 1 and outcome during sepsis. 1, 2 Genetic
polymorphisms represent interindividual genetic variability and may help to explain host …

Background. Candida bloodstream infections cause significant morbidity and mortality
among hospitalized patients. Although clinical and microbiological factors affecting …

Background Sixteen melanoma patients (1 stage IIC, 8 stage III, and 7 stage IV) were treated
in a Phase I study with a vaccine (DC/Apo-Nec) composed of autologous dendritic cells …

Critically ill patients with sepsis require a multidisciplinary approach, as this situation implies
multiorgan distress, with most of the bodily biochemical and cellular systems being affected …

No clear consensus has been reached regarding the association of IL-10 polymorphisms
and periodontitis. Therefore, we performed a meta-analysis of case–control studies and a …

Background: Interleukin-10 (IL-10) is an anti-inflammatory cytokine that has important roles
in the periodontal diseases. The IL10-1082,-819, and-592 polymorphisms in the promoter …