Chalcone: a privileged structure in medicinal chemistry
Privileged structures have been widely used as an effective template in medicinal chemistry
for drug discovery. Chalcone is a common simple scaffold found in many naturally occurring …
for drug discovery. Chalcone is a common simple scaffold found in many naturally occurring …
Recent developments in biological activities of chalcones: A mini review
Chalcones represent key structural motif in the plethora of biologically active molecules
including synthetic and natural products. Synthetic manipulations of chalcones or their …
including synthetic and natural products. Synthetic manipulations of chalcones or their …
Anti-cancer chalcones: Structural and molecular target perspectives
Abstract Chalcone or (E)-1, 3-diphenyl-2-propene-1-one scaffold remained a fascination
among researchers in the 21st century due to its simple chemistry, ease of synthesis and a …
among researchers in the 21st century due to its simple chemistry, ease of synthesis and a …
Recent advances (2015–2016) in anticancer hybrids
In spite of the development of a large number of novel anticancer drugs over the years,
Cancer remains as a prominent cause of death, worldwide. Numerous drugs that are …
Cancer remains as a prominent cause of death, worldwide. Numerous drugs that are …
Antitumoral activity of quinoxaline derivatives: A systematic review
M Montana, F Mathias, T Terme, P Vanelle - European journal of medicinal …, 2019 - Elsevier
Cancer is a leading cause of death and a major health problem worldwide. While many
effective anticancer agents are available, the majority of drugs currently on the market are …
effective anticancer agents are available, the majority of drugs currently on the market are …
Advances in chalcones with anticancer activities
C Karthikeyan, N SH Narayana Moorthy… - Recent patents on …, 2015 - ingentaconnect.com
Chalcones are naturally occurring compounds exhibiting broad spectrum biological
activities including anticancer activity through multiple mechanisms. Literature on anticancer …
activities including anticancer activity through multiple mechanisms. Literature on anticancer …
Quinoxaline: An insight into the recent pharmacological advances
S Tariq, K Somakala, M Amir - European Journal of Medicinal Chemistry, 2018 - Elsevier
Quinoxaline, a fused heterocycle of benzene and pyrazine rings has gained considerable
attention in the field of contemporary medicinal chemistry. The moiety is of substantial …
attention in the field of contemporary medicinal chemistry. The moiety is of substantial …
[HTML][HTML] Quinoxaline: A comprehension of current pharmacological advancement in medicinal chemistry
SK Suthar, NS Chundawat, GP Singh… - European Journal of …, 2022 - Elsevier
Quinoxaline is a fused heterocycle ring template present in diverse pharmacophore and
widely used in medicinal chemistry. Owing to its vast pharmaceutical profile, several …
widely used in medicinal chemistry. Owing to its vast pharmaceutical profile, several …
An insight into medicinal chemistry of anticancer quinoxalines
T Kaushal, G Srivastava, A Sharma, AS Negi - Bioorganic & Medicinal …, 2019 - Elsevier
Quinoxalines are benzopyrazines containing benzene and pyrazine rings fused together. In
the recent past, quinoxalines have attracted Medicinal Chemists considerably for their …
the recent past, quinoxalines have attracted Medicinal Chemists considerably for their …
Targeting the PI3K/AKT/mTOR signaling pathway in glioblastoma: novel therapeutic agents and advances in understanding
A Sami, M Karsy - Tumor Biology, 2013 - Springer
Glioblastoma multiforme (GBM) is a grade IV astrocytoma with a median survival of 12
months despite current multi-modal treatment options. GBM is distinguished …
months despite current multi-modal treatment options. GBM is distinguished …