Herein recent progress in developing red blood cell (RBC)‐inspired delivery systems is
reviewed, with an emphasis on how our growing understanding of fundamental biological …

The complement system, a pillar of innate immunity, has belatedly become recognised as a
key modulator of adaptive immunity, acting to direct, modulate and modify the responses of …

Decay-accelerating factor ([DAF] CD55) is a glycosylphosphatidylinositol-anchored
membrane inhibitor of complement with broad clinical relevance. Here, we establish an …

Human pancreatic islets highly express CD59, which is a glycosylphosphatidylinositol (GPI)-
anchored cell-surface protein and is required for insulin secretion. How cell-surface CD59 …

CD59 was first identified as a regulator of the terminal pathway of complement, which acts
by binding to the C8/C9 components of the assembling membrane attack complex (MAC), to …

Renal ischemia-reperfusion injury (IRI) is a feature of ischemic acute renal failure and it
impacts both short-and long-term graft survival after kidney transplantation. Complement …

The aim of our study was to clarify the association between immunoglobulin G (IgG)
subclasses and the complement pathway in patients with idiopathic membranous …

Background: We previously reported the existence of complement activation through the
alternative and lectin pathways in patients with immunoglobulin A (IgA) glomerulonephritis …

Activation of complement is a key determinant of neuropathology and disability after
traumatic brain injury (TBI), and inhibition is neuroprotective. However, systemic …

CD59 has been identified as a glycosylphosphatidylinositol-anchored membrane protein
that acts as an inhibitor of the formation of the membrane attack complex to regulate …