Chemical RNA cross-linking: mechanisms, computational analysis, and biological applications

WA Velema, Z Lu - Jacs Au, 2023 - ACS Publications
In recent years, RNA has emerged as a multifaceted biomolecule that is involved in virtually
every function of the cell and is critical for human health. This has led to a substantial …

A Hitchhiker's guide to RNA–RNA structure and interaction prediction tools

FYF Tieng, MR Abdullah-Zawawi… - Briefings in …, 2024 - academic.oup.com
RNA biology has risen to prominence after a remarkable discovery of diverse functions of
noncoding RNA (ncRNA). Most untranslated transcripts often exert their regulatory functions …

RNA interaction format: a general data format for RNA interactions

RA Schäfer, D Rabsch, GE Scholz, PF Stadler… - …, 2023 - academic.oup.com
RNA molecules play crucial roles in various biological processes. They mediate their
function mainly by interacting with other RNAs or proteins. At present, information about …

[HTML][HTML] Limits of experimental evidence in RNA secondary structure prediction

S von Löhneysen, M Mörl, PF Stadler - Frontiers in Bioinformatics, 2024 - frontiersin.org
Chemical and enzymatic probing has a long history as an experimental source of
information on RNA secondary structures. In recent years such protocols were interfaced …

CheRRI—Accurate classification of the biological relevance of putative RNA–RNA interaction sites

T Müller, S Mautner, P Videm, F Eggenhofer… - …, 2024 - academic.oup.com
Background RNA–RNA interactions are key to a wide range of cellular functions. The
detection of potential interactions helps to understand the underlying processes. However …

Bioinformatic and experimental methods to identify and validate bacterial RNA-human RNA interactions

KI Krohmaly, RJ Freishtat… - Journal of Investigative …, 2023 - journals.sagepub.com
Ample evidence supports the importance of the microbiota on human health and disease.
Recent studies suggest that extracellular vesicles are an important means of bacterial-host …

SCRAP: a bioinformatic pipeline for the analysis of small chimeric RNA-seq data

WT Mills, S Eadara, AE Jaffe, MK Meffert - RNA, 2023 - rnajournal.cshlp.org
MicroRNAs (miRNAs) are small noncoding RNAs (sncRNAs) that function in post-
transcriptional gene regulation through imperfect base pairing with mRNA targets, which …