Acute myeloid leukemia (AML) is the most common acute leukemia in adults, with an
incidence of over 20 000 cases per year in the United States alone. Large chromosomal …

Nuclear clearance and cytoplasmic mislocalization of the essential RNA binding protein,
TDP-43, is a pathologic hallmark of amyotrophic lateral sclerosis, frontotemporal dementia …

Streptomyces bacteria are known for their prolific production of secondary metabolites, many
of which have been widely used in human medicine, agriculture and animal health. To guide …

The treatment of acute myeloid leukemia (AML) has evolved over the past few years with the
advent of next-generation sequencing. Targeted therapies alone or in combination with low …

Anthracyclines remain a cornerstone of induction chemotherapy for acute myeloid leukemia
(AML). Refractory or relapsed disease due to chemotherapy resistance is a major obstacle …

Acute myeloid leukemia (AML) is a clonal disorder of hematopoietic progenitor cells and the
most common malignant myeloid disorder in adults. Several gene mutations such as in …

Pediatric acute myeloid leukemia (AML) is a heterogeneous disease that requires a
multifaceted treatment approach. Although outcomes for low‐risk AML have improved …

Background Leukemia, a cancer impacting blood-forming tissues such as bone marrow and
the lymphatic system, presents in various forms, affecting children and adults differently. The …

Objective: To ascertain the efficacy and safety of daunorubicin combined with cytarabine
comparing with idarubicin combined with cytarabine as a standard induction therapy for …

Anthracyclines amount to one of the most effective and wellknown chemotherapeutic agents
used for cancer treatment. However, a range of adverse effects, including cardiotoxicity and …