The present work aims to examine the worrying problem of antibiotic resistance and the
emergence of multidrug-resistant bacterial strains, which have now become really common …

Pseudomonas aeruginosa is an important Gram-negative opportunistic pathogen which
causes many severe acute and chronic infections with high morbidity, and mortality rates as …

Infections due to multidrug-resistant Enterobacteriaceae have become major international
public health problem due to the inadequate treatment options and the historically lagged …

Carbapenems are considered as last-resort antibiotics for the treatment of infections caused
by multidrug-resistant Gram-negative bacteria. With the increasing use of carbapenems in …

This chapter analyzes the epidemiology of Carbapenem-Resistant Enterobacteriaceae
(CRE) as well as current and future treatment options against the increasingly resistant …

The discovery of antibiotics has long been regarded as one of the most significant medical
achievements of the twentieth century. Antibiotics have saved millions of lives (1) and …

ESKAPE pathogens (Enterococcus faecium, Staphylococcus aureus, Klebsiella
pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter …

The tetracycline antibiotic class has acquired new valuable members due to the optimisation
of the chemical structure. The first modern tetracycline introduced into therapy was …

Carbapenem-resistant Acinetobacter baumannii (CRAB) is a perilous nosocomial pathogen
causing substantial morbidity and mortality. Current treatment options for CRAB are limited …

The progressive increase in antibiotic resistance in recent decades calls for urgent
development of new antibiotics and antibiotic stewardship programs to help select …