Acute kidney injury (AKI) is the leading cause of nephrology consultation and is associated
with high mortality rates. The primary causes of AKI include ischemia, hypoxia or …

Ischemia-reperfusion injury (IRI) during renal transplantation often initiates non-specific
inflammatory responses that can result in the loss of kidney graft viability. However, the long …

Surgery is an important treatment modality for the majority of solid organ cancers.
Unfortunately, cancer recurrence following surgery of curative intent is common, and …

Renal fibrosis is the common outcome of many chronic kidney diseases (CKD) independent
of the underlying etiology. Despite a host of promising experimental data, currently available …

Recent clinical and animal studies have shown that acute kidney injury (AKI), even if
followed by complete recovery of renal function, can eventually result in chronic kidney …

Introduction Acute kidney injury following surgery incurs significant mortality with no proven
preventative therapy. We investigated whether the α 2 adrenoceptor agonist …

Surgery is of paramount importance in the management of solid tumors as definitive
resection can be totally curative. Nonetheless, metastatic recurrence after surgery remains a …

Background: Surgery is considered to be the first line treatment for solid tumours. Recently,
retrospective studies reported that general anaesthesia was associated with worse long …

General anesthetics are commonly used in major surgery. To achieve the depth of
anesthesia for surgery, patients are being subjected to a variety of general anesthetics …

Renal ischemia-reperfusion injury (IRI) is a significant clinical challenge faced by clinicians
perioperatively in kidney transplantation. Recent work has demonstrated the key importance …